Klotho gene-modified BMSCs showed elevated antifibrotic effects by inhibiting the Wnt/β-catenin pathway in kidneys after acute injury

Author:

Zhang Feng12ORCID,Wan Xin2,Cao Yi-Zhi3,Sun Dong2,Cao Chang-Chun1

Affiliation:

1. Department of Nephrology; Sir Run Run Hospital; Nanjing Medical University; Nanjing 211166 China

2. Department of Nephrology; Nanjing First Hospital; Nanjing Medical University; Nanjing 210006 China

3. The First School of Clinical Medicine; Nanjing Medical University; Nanjing 211166 China

Funder

National Natural Science Foundation of China

the 333 project in Jiangsu Province

Publisher

Wiley

Subject

Cell Biology,General Medicine

Reference28 articles.

1. Intraparenchymal injection of bone marrow mesenchymal stem cells reduces kidney fibrosis after ischemia-reperfusion in cyclosporine-immunosuppressed rats;Alfarano;Cell Transplant,2012

2. Macrophages in kidney injury, inflammation, and fibrosis;Cao;Physiology (Bethesda),2015

3. Chronic kidney disease after acute kidney injury: a systematic review and meta-analysis;Coca;Kidney Int,2012

4. A regulatory miRNA-mRNA network is associated with tissue repair induced by mesenchymal stromal cells in acute kidney injury;de Almeida;Front Immunol,2016

5. Klotho inhibits transforming growth factor-beta1 (TGF-beta1) signaling and suppresses renal fibrosis and cancer metastasis in mice;Doi;J Biol Chem,2011

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3