American Registry of Ambulatory or acutely decompensated heart failure (AMERICCAASS Registry): First 1000 patients

Author:

Gómez‐Mesa Juan Esteban123ORCID,Gutiérrez‐Posso Juliana María3ORCID,Escalante‐Forero Manuela3ORCID,Córdoba‐Melo Brayan Daniel3ORCID,Cárdenas‐Marín Paula Andrea12ORCID,Perna Eduardo R.4ORCID,Valle‐Ramos Mádelyn Raquel5ORCID,Giraldo‐González Germán Camilo6ORCID,Flórez‐Alarcón Noel Alberto2ORCID,Rodríguez‐Caballero Ida Fabiola7ORCID,Núñez‐Carrizo Cristian89ORCID,Cabral‐Gueyraud Luz Teresa10ORCID,Marte‐Arias Sarah Raquel11ORCID,Hardin Elizabeth Ashley12,Álvarez‐Sangabriel Amada13ORCID,Menjívar‐De Ramos María Eugenia14,van der Hilst Kwame1516ORCID,Cruz‐Díaz Licurgo Jacob17,Fausto Ovando Sergio Roberto18ORCID,Rodríguez Luis Arturo19ORCID,Escalante Juan Pablo20ORCID,Ormaechea‐Gorricho Gabriela21ORCID,Bornancini Norberto Raul22,Rodríguez‐González María Juliana23ORCID,Campbell‐Quintero Sebastián24ORCID,González‐Hormostay Raquel E.252627,Oviedo‐Pereira Guillermo28,Trout‐Guardiola Guillermo29ORCID,Encina Juan Justiniano30,Jerez‐Castro Ana Margarita31ORCID,Drazner Mark32ORCID,Quesada‐Chaves Daniel33ORCID,Romero‐Guerra Alexander34ORCID,Rossel‐Mariángel Víctor Alejandro3536ORCID,Speranza Mario37ORCID

Affiliation:

1. Department of Cardiology Fundación Valle del Lili Cali Colombia

2. Department of Health Sciences Universidad Icesi Cali Colombia

3. Fundación Valle del Lili Centro de investigaciones Clínicas Cali Colombia

4. Instituto De Cardiología J. F. Cabral Department of Heart Failure and Pulmonary Hypertension Corrientes Argentina

5. Department of Internal Medicine Hospital Regional de Zacapa Ciudad de Zacapa Guatemala

6. Department of Cardiology Todo por el Corazón cardiology center Manizales Colombia

7. Instituto Nacional de Cardiología “Prof. Dr. Juan Adolfo Cattonni” Asunción Paraguay

8. Clínica El Castaño Multipurpose Unit, Echocardiography and Ambulatory San Juan Argentina

9. CIMAC, Multipurpose Unit, Echocardiography and Ambulatory San Juan Argentina

10. Hospital Nacional de Itaugua, Department of Cardiology Itaugua Paraguay

11. Department of Cardiology Clínica Universitaria Unión Médica del Norte Santiago Dominican Republic

12. Department of Internal Medicine University of Texas Southwestern Medical Center Dallas Texas USA

13. Emergency Department and Coronary Care Unit Instituto Nacional de Cardiología Ignacio Chávez Mexico city Mexico

14. Department of Cardiology Centro de Cardiología y Ortopedia (CCO) San Salvador El Salvador

15. Department of Cardiology Thorax Center Paramaribo Paramaribo Suriname

16. Department of Cardiology Academic Hospital Paramaribo Paramaribo Suriname

17. Department of Cardiology Hospital Regional Universitario “Presidente Estrella Ureña” Santiago Dominican Republic

18. Department of Cardiology Cardiocentro Chimaltenango Chimaltenango Guatemala

19. Cardiology Unit Hospital Roosevelt Guatemala city Guatemala

20. Instituto Cardiovascular de Rosario, Heart Failure Transplantation and Pulmonary Hypertension Unit Rosario Argentina

21. Department of Internal Medicine Hospital de Clínicas “Dr. Manuel Quintela” Montevideo Uruguay

22. Department of Cardiology Centro Médico Talar Buenos Aires Argentina

23. Department of Heart Failure and Transplantation LaCardio Bogota Colombia

24. Department of Cardiology Clínica Medilaser Florencia Colombia

25. ASCARDIO, Heart Failure Unit Barquisimeto Venezuela

26. ASCARDIO, Coronary Intensive Care Unit Barquisimeto Venezuela

27. ASCARDIO, Echocardiography Laboratory Barquisimeto Venezuela

28. Department of Internal Medicine Instituto De Previsión Social Asuncion Paraguay

29. Department of Cardiology GrupSalud Santa Marta Colombia

30. Hospital Universitario Japonés, Department of Medicine Santa Cruz de la Sierra Bolivia

31. Department of Cardiology Instituto de Cardiología y Cirugía Cardiovascular La Habana Cuba

32. Department of Cardiology University of Texas Southwestern Medical Center Dallas Texas USA

33. Department of Cardiology Hospital San Vicente de Paul Heredia Costa Rica

34. Department of Cardiology Hospital Santo Tomas Panama City Panama

35. Department of Cardiology Hospital del Salvador Santiago Chile

36. Department of Cardiology Instituto Nacional del Tórax Santiago Chile

37. Department of Cardiology Hospital Clínica Bíblica San Jose Costa Rica

Abstract

AbstractBackgroundAbout 80% of cardiovascular diseases (including heart failure [HF]) occur in low‐income and developing countries. However, most clinical trials are conducted in developed countries.HypothesisThe American Registry of Ambulatory or Acutely Decompensated Heart Failure (AMERICCAASS) aims to describe the sociodemographic characteristics of HF, comorbidities, clinical presentation, and pharmacological management of patients with ambulatory or acutely decompensated HF in America.MethodologyDescriptive, observational, prospective, and multicenter registry, which includes patients >18 years with HF in an outpatient or hospital setting. Collected information is stored in the REDCap electronic platform. Quantitative variables are defined according to the normality of the variable using the Shapiro–Wilk test.ResultsThis analysis includes data from the first 1000 patients recruited. 63.5% were men, the median age of 66 years (interquartile range 56.7–75.4), and 77.6% of the patients were older than 55 years old. The percentage of use of the four pharmacological pillars at the time of recruitment was 70.7% for beta‐blockers (BB), 77.4% for angiotensin‐converting enzyme inhibitor (ACEI)/angiotensin II receptor blocker (ARB II)/angiotensin receptor‐neprilysin inhibitor (ARNI), 56.8% for mineralocorticoid receptor antagonists (MRA), and 30.7% for sodium–glucose cotransporter type‐2 inhibitors (SGLT2i). The main cause of decompensation in hospitalized patients was HF progression (64.4%), and the predominant hemodynamic profile was wet‐warm (68.3%).ConclusionsAMERICCAASS is the first continental registry to include hospitalized or outpatient patients with HF. Regarding optimal medical therapy, approximately a quarter of the patients still need to receive BB and ACEI/ARB/ARNI, less than half do not receive MRA, and more than two‐thirds do not receive SGLT2i.

Publisher

Wiley

Subject

Cardiology and Cardiovascular Medicine,General Medicine

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