Preoperative systemic levels of VEGFA, IL-7, IL-17A, and TNF-β delineate two distinct groups of children with brain tumors

Author:

Sandén Emma1,Enríquez Pérez Julio1,Visse Edward1,Kool Marcel2,Carén Helena3,Siesjö Peter14,Darabi Anna1

Affiliation:

1. Glioma Immunotherapy Group, Faculty of Medicine, Department of Clinical Sciences Lund, Neurosurgery; Lund University; Lund Sweden

2. Division of Pediatric Neurooncology; German Cancer Research Center DKFZ; Heidelberg Germany

3. Sahlgrenska Cancer Center; Department of Pathology; Institute of Biomedicine; University of Gothenburg; Gothenburg Sweden

4. Department of Clinical Sciences Lund; Neurosurgery; Lund University; Skåne University Hospital; Lund Sweden

Funder

Barncancerfonden

Network for Neuroblastoma and CNS tumor research in children

Skåne University Hospital donation funds

Governmental funding of clinical research within the national health services

Kungliga Fysiografiska Sällskapet i Lund

Svenska Läkaresällskapet

Lions Skåne Research Foundation

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Reference46 articles.

1. CBTRUS statistical report: Primary brain and central nervous system tumors diagnosed in the United States in 2007-2011;Ostrom;Neuroncology,2014

2. Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma;Lambert;Acta Neuropathol,2013

3. Medulloblastoma comprises four distinct molecular variants;Northcott;J Clin Oncol,2011

4. Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma;Sturm;Cancer Cell,2012

5. Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma;Witt;Cancer Cell,2011

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