Robotic versus laparoscopic distal pancreatectomy for pancreatic adenocarcinoma in obese patients

Author:

Ausania Fabio1,Landi Filippo1,González‐Abós Carolina1,Martinie John B.2,Vrochides Dionisios2,Walsh Matthew3,Hossain Shanaz M.3,White Steven4,Prabakaran Viswakumar4,Melstrom Laleh G.5,Fong Yuman5,Valle Valentina6ORCID,Bing Yuntao7,Xiu Dianrong7,Di Franco Gregorio8,de' Angelis Nicola9ORCID,Laurent Alexis9,Giuliani Giuseppe10,Pernazza Graziano11ORCID,Memeo Riccardo12,Rios José13,Coratti Andrea10,Morelli Luca8ORCID,Giulianotti Pier C.6

Affiliation:

1. Department of HBP Surgery and Transplantation Hospital Clinic Barcelona Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) University of Barcelona (UB) Barcelona Spain

2. Department of Surgery Division of HPB Surgery Carolinas Medical Center Charlotte North Carolina USA

3. HPB Surgery Department Digestive Disease and Surgery Institute Cleveland Clinic Cleveland Ohio USA

4. Freeman Hospital NHS Newcastle‐Upon‐Tyne UK

5. Division of Surgical Oncology Gastrointestinal Disease Team City of Hope Medical Center Duarte California USA

6. Department of Surgery Division of General, Minimally Invasive and Robotic Surgery University of Illinois at Chicago Chicago Illinois USA

7. Department of General Surgery Beijing Third Hospital Beijing China

8. Division of Translational and New Technologies in Medicine and Surgery General Surgery Department University of Pisa Pisa Italy

9. Department of Digestive HBP Surgery and Liver Transplantation Henri Mondor Hospital APHP Creteil France

10. Division of General and Minimally Invasive Surgery Misericordia Hospital Grosseto Italy

11. General and Robotic Surgery Department San Giovanni Hospital Rome Italy

12. Department of Surgery Acquaviva delle Fonti Hospital Bari Italy

13. Department of Clinical Pharmacology Hospital Clinic and Medical Statistics Core Facility Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) Biostatistics Unit Faculty of Medicine Universitat Autònoma de Barcelona (UAB) Barcelona Spain

Abstract

AbstractBackgroundRobotic distal pancreatectomy (RDP) is associated with a lower conversion rate and less blood loss than laparoscopic distal pancreatectomy (LDP). LDP has similar oncological outcomes as open surgery in PDAC. The aim of this study was to compare perioperative and oncological outcomes in obese patients with RDP versus LDP for PDAC.Materials and methodsRetrospectively, all obese patients who underwent RDP or LDP for PDAC between 2012 and 2022 at 12 international expert centres were included.Resultsout of 372, 81 patients were included. All baseline features were comparable between the two groups. RDP was associated with decreased blood loss (495mlLDP vs. 188mlRDP; p = 0.003), lower conversion rate (13.5%RDP vs. 36.4%LDP; p = 0.019) and lower rate of Clavien‐Dindo ≥3 complications (13.5%RDP vs. 36.4%LDP; p = 0.019). Overall and disease‐free survival were comparable.ConclusionsIn obese patients with left‐sided PDAC, the robotic approach was associated with improved intraoperative outcomes and fewer severe complications.

Publisher

Wiley

Subject

Computer Science Applications,Biophysics,Surgery

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