A novel protein-based prognostic signature improves risk stratification to guide clinical management in early-stage lung adenocarcinoma patients

Author:

Martínez-Terroba Elena12,Behrens Carmen3,de Miguel Fernando J14,Agorreta Jackeline1256,Monsó Eduard78,Millares Laura78,Sainz Cristina16,Mesa-Guzman Miguel59,Pérez-Gracia José Luis5610,Lozano María Dolores5611,Zulueta Javier J5612,Pio Ruben1456,Wistuba Ignacio I313,Montuenga Luis M1256,Pajares María J1256ORCID

Affiliation:

1. Program in Solid Tumours, CIMA; Pamplona Spain

2. Department of Histology and Pathology, School of Medicine; University of Navarra; Pamplona Spain

3. Department of Thoracic/Head and Neck Medical Oncology; The University of Texas MD Anderson Cancer Center; Houston TX USA

4. Department of Biochemistry and Genetics, School of Sciences; University of Navarra; Pamplona Spain

5. Navarra Health Research Institute (IDISNA); Pamplona Spain

6. Centro de Investigación Biomédica en Red de Cáncer (CIBERONC); Madrid Spain

7. Respiratory Diseases Department; Parc Taulí University Hospital; Sabadell, Barcelona Spain

8. Ciber de Enfermedades Respiratorias - CIBERES, Instituto de Salud Carlos III; Madrid Spain

9. Department of Thoracic Surgery; Clínica Universidad de Navarra; Pamplona Spain

10. Department of Oncology; Clínica Universidad de Navarra; Pamplona Spain

11. Department of Pathology; Clínica Universidad de Navarra; Pamplona Spain

12. Department of Neumology; Clínica Universidad de Navarra; Pamplona Spain

13. Department of Translational Molecular Pathology; The University of Texas, MD Anderson Cancer Center; Houston TX USA

Funder

AECC Scientific Foundation

Ciber de Enfermedades Respiratorias-CIBERES-FEDER

CIBERONC

FIMA

Sociedad Española de Neumología y Cirugía Torácica

Spanish Ministry of Economy and Innovation and Fondo de Investigación Sanitaria-Fondo Europeo de Desarrollo Regional

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference50 articles.

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2. Recurrence after surgery in patients with NSCLC;Uramoto;Transl Lung Cancer Res,2014

3. Postoperative adjuvant systemic therapy in completely resected non-small-cell lung cancer: a systematic review;Bradbury;Clin Lung Cancer,2017

4. Low-dose computed tomography for lung cancer screening: clinical and coding considerations;Shieh;Chest,2017

5. Reduced lung-cancer mortality with low-dose computed tomographic screening;Aberle;N Engl J Med,2011

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