Determination of sunitinib and its active metabolite,N-desethyl sunitinib in mouse plasma and tissues by UPLC-MS/MS: assay development and application to pharmacokinetic and tissue distribution studies-Reference-Cited by-同舟云学术

Determination of sunitinib and its active metabolite,N-desethyl sunitinib in mouse plasma and tissues by UPLC-MS/MS: assay development and application to pharmacokinetic and tissue distribution studies

Published:2014-10-08 Issue:5 Volume:29 Page:679-688
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomed. Chromatogr.

Author:

Chen Xiao¹,Wang Zhong²³,Liu Mengping¹,Liao Min¹,Wang Xinfeng¹,Du Huajuan¹,Chen Jiefeng¹,Yao Meicun¹,Li Qing²³

Affiliation:

1. Pharmaceutical Analysis Laboratory, School of Pharmaceutical Sciences; Sun Yat-sen University; 132 Waihuan Road East Guangzhou 510006 China

2. The Center for Cellular and Structural Biology; Sun Yat-sen University; 132 Waihuan Road East Guangzhou 510006 China

3. Kornberg Group, School of Pharmaceutical Sciences; Sun Yat-sen University; 132 Waihuan Road East Guangzhou 510006 China

Funder

Grant for Introduced Innovative R&D Team Leadership of Guangdong Province

Grant for the Laboratory Open-end Fund in 2013 of Sun Yat-Sen University

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

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5. A validated assay for the simultaneous quantification of six tyrosine kinase inhibitors and two active metabolites in human serum using liquid chromatography coupled with tandem mass spectrometry;Erp;Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences,2013

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