Thermal lactonization of brominated alkylidenemalonates: Synthesis of 2‐buten‐4‐olides-Reference-Cited by-同舟云学术

Thermal lactonization of brominated alkylidenemalonates: Synthesis of 2‐buten‐4‐olides

Published:1978-01 Issue:3 Volume:87 Page:215-222
ISSN:0037-9646
Container-title:Bulletin des Sociétés Chimiques Belges
language:en
Short-container-title:Bulletin des Soc Chimique

Author:

Verhé Roland,De Kimpe Norbert,De Buyck Laurent,Courtheyn Dirk,Schamp Niceas

Abstract

AbstractHeating of dialkyl 2‐bromoalkylidenemalonates in boiling xylene resulted in lactonization with formation of 2‐alkoxycarbonyl‐2‐buten‐4‐olides. Bromination of dimethyl 2‐phenylpropylidenemalonate with NBS in CCI4 gave the corresponding butenolide. However, heating of the 2‐bromocyclohexylidenemalonate only afforded the dehydrobromination product.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bscb.19780870309

Reference19 articles.

1. Nucleophilic Substitution Reactions of Brominated Dimethyl Alkylidene Malonates

2. Physiologically active unsatured lactones

3. .alpha.-Methylene lactones. IX. Oxygenated .alpha.-methylene-.gamma.-butyrolactones

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