Machine learning algorithms for outcome prediction in (chemo)radiotherapy: An empirical comparison of classifiers

Author:

Deist Timo M.12,Dankers Frank J. W. M.23,Valdes Gilmer4,Wijsman Robin3,Hsu I‐Chow4,Oberije Cary2,Lustberg Tim5,Soest Johan5,Hoebers Frank5,Jochems Arthur12,El Naqa Issam6,Wee Leonard5,Morin Olivier4,Raleigh David R.4,Bots Wouter37,Kaanders Johannes H.3,Belderbos José8,Kwint Margriet8,Solberg Timothy4,Monshouwer René3,Bussink Johan3,Dekker Andre5,Lambin Philippe1

Affiliation:

1. The D‐lab: Decision Support for Precision Medicine GROW ‐ School for Oncology and Developmental Biology Maastricht University Medical Centre+ Universiteitssingel 40 6229 ER Maastricht The Netherlands

2. Department of Radiation Oncology GROW, School for Oncology and Developmental Biology Maastricht University Medical Center Maastricht The Netherlands

3. Department of Radiation Oncology Radboud University Medical Center Nijmegen The Netherlands

4. Department of Radiation Oncology University of California San Francisco San Francisco CA USA

5. Department of Radiation Oncology (MAASTRO) GROW, School for Oncology and Developmental Biology Maastricht University Medical Center Maastricht The Netherlands

6. Department of Radiation Oncology University of Michigan Ann Arbor Michigan USA

7. Institute for Hyperbaric Oxygen (IvHG) Arnhem The Netherlands

8. Department of Radiation Oncology The Netherlands Cancer Institute–Antoni van Leeuwenhoek Hospital Amsterdam The Netherlands

Funder

H2020 European Research Council

Stichting voor de Technische Wetenschappen

Ministerie van Economische Zaken

Seventh Framework Programme

H2020 Innovation In SMEs

KWF Kankerbestrijding

Kurt Weill Foundation for Music

Nanjing Forestry University

Varian Medical Systems

Publisher

Wiley

Subject

General Medicine

Reference34 articles.

1. Predicting outcomes in radiation oncology—multifactorial decision support systems

2. ‘Rapid Learning health care in oncology’ – An approach towards decision support systems enabling customised radiotherapy’

3. KuhnM WingJ WestonS et al.Caret: Classification and Regression Training;2016.https://CRAN.R-project.org/package=caret.

4. Do we need hundreds of classifiers to solve real world classification problems?;Fernández‐Delgado M;J Mach Learn Res,2014

5. WainerJ.Comparison of 14 different families of classification algorithms on 115 binary datasets. ArXiv160600930 Cs. June2016.http://arxiv.org/abs/1606.00930. Accessed April 8 2017.

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