Trends in the incidence of colorectal cancer in sub‐Saharan Africa: A population‐based registry study

Author:

Moen Laura1,Liu Biying2,Bukirwa Phiona3,Chingonzoh Tatenda4,Chokunonga Eric5,Finesse Anne6,Korir Ann7,Lamin Bojang8,Lorenzoni Cesaltina Ferreira9,Manraj Shyam S.10,N'Da Guy11,Odzebe Anani Wencesl Severin12,Ogunbiyi Olufemi13,Somdyala Nontuthuzelo I. M.14ORCID,Packzowski Magdalena15,Parkin Donald M.21617ORCID

Affiliation:

1. CUNY School of Public Health and Health Policy New York New York USA

2. African Cancer Registry Network Oxford UK

3. Kampala Cancer Registry Makerere University School of Medicine Kampala Uganda

4. Bulawayo Cancer Registry Bulawayo Zimbabwe

5. Zimbabwe National Cancer Registry Harare Zimbabwe

6. Seychelles National Cancer Registry Victoria Seychelles

7. National Cancer Registry Kenya Medical Research Institute Nairobi Kenya

8. Gambia National Cancer Registry Fajara Gambia

9. Department of Pathology, Faculty of Medicine Eduardo Mondlane University, Maputo Central Hospital Maputo Mozambique

10. Mauritius National Cancer Registry Pt Louis Mauritius

11. Registre des cancers d'Abidjan Abidjan Côte d'Ivoire

12. Registre des cancers de Brazzaville Brazzaville Republique du Congo

13. Ibadan Cancer Registry Ibadan Nigeria

14. South African Medical Research Council Eastern Cape Cancer Registry Tygerberg South Africa

15. Vital Strategies New York New York USA

16. Cancer Surveillance Unit International Agency for Research on Cancer Lyon France

17. Nuffield Department of Medicine University of Oxford Oxford UK

Abstract

AbstractIn sub‐Saharan Africa, colorectal cancer (CRC) has historically been considered a rare disease, although some previous studies have suggested that the incidence is increasing. We examine time trends in the incidence of CRC using data from 12 population‐based cancer registries in 11 countries of sub‐Saharan Africa that were able to provide time series data for periods of 12 or more years, or with earlier data with which recent rates may be compared. Age‐standardized incidence rates were highest in the higher‐income countries, and were increasing in all of the populations studied, and these increases were statistically significant in all but three. Current evidence has suggested a link between the increased adoption of western lifestyle habits with colorectal cancer, and along with increasing urbanization of African populations, there is an increase in body weight, as well as evidence of increasing consumption of meat, sugars, and alcohol.

Publisher

Wiley

Reference36 articles.

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2. World Cancer Research Fund (WCRF).Third Expert Report Diet Nutrition Physical Activity and Cancer: a Global Perspective Continuous Update Expert Report.2018https://www.wcrf.org/diet‐activity‐and‐cancer/global‐cancer‐update‐programme/about‐the‐third‐expert‐report/

3. Dietary Fiber and Colorectal Cancer Risk: A Nested Case-Control Study Using Food Diaries

4. A review of human carcinogens—Part E: tobacco, areca nut, alcohol, coal smoke, and salted fish

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