Loss of TSC1 in secondary angiosarcoma of the breast-Reference-Cited by-同舟云学术

Loss of TSC1 in secondary angiosarcoma of the breast

Published:2023-07 Issue:7 Volume:11 Page:
ISSN:2050-0904
Container-title:Clinical Case Reports
language:en
Short-container-title:Clinical Case Reports

Author:

Rose Lucy¹^ORCID,Owusu‐Brackett Nicci¹^ORCID,Moore Stephen²,Oppong Bridget¹^ORCID

Affiliation:

1. Division of Surgical Oncology, Department of Surgery The Ohio State University Wexner Medical Center Columbus Ohio USA

2. Department of Pathology The Ohio State University Wexner Medical Center Columbus Ohio USA

Abstract

Key Clinical MessagePost‐radiation angiosarcoma of the breast is a rare complication associated with a poor prognosis. This case reports the first loss of function mutation in TSC1 in breast radiation‐induced angiosarcoma and illustrates the utility of evaluating these markers to identify potential therapeutic targets.AbstractPost‐radiation angiosarcoma of the breast is rare and associated with a poor prognosis. This case presents the first loss of function mutation in TSC1 in breast radiation‐induced angiosarcoma. Evaluation of these markers can aid in identifying potential therapeutic targets.

Publisher

Wiley

Subject

General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ccr3.7539

Reference10 articles.

1. Long-term radiation complications following conservative surgery (CS) and radiation therapy (RT) in patients with early stage breast cancer

2. Cutaneous Radiation-Associated Angiosarcoma of the Breast: Poor Prognosis in a Rare Secondary Malignancy

3. Radiation-induced Stromal Sarcoma of Breast: A Case Report and Literature Review

4. Radiation dose and risk of soft tissue and bone sarcoma after breast cancer treatment

5. Pathologic Angiogenesis of Malignant Vascular Sarcomas: Implications for Treatment