Association of lactate/albumin ratio with 3‐month readmission risk in heart failure patients: a retrospective study

Author:

Sun Hui12,Wang Baiqiang1,An Guipeng1,Zhang Yun1,Ma Lianyue1ORCID

Affiliation:

1. Department of Cardiology, National Key Laboratory for Innovation and Transformation of Luobing Theory, The Key Laboratory of Cardiovascular Remodeling and Function Research, Chinese Ministry of Education, Chinese National Health Commission and Chinese Academy of Medical Sciences Qilu Hospital of Shandong University Jinan China

2. Department of Cardiology, Qilu Hospital (Qingdao) Qilu Hospital of Shandong University Qingdao China

Abstract

AbstractAimsThe predictive value of the lactate/albumin ratio (LAR) in mortality is established in various conditions, yet its relevance to 3‐month readmission risk in Chinese adults with heart failure (HF) remains unclear.Method and resultsAnalysing data from 957 patients with HF at Zigong Fourth People's Hospital, Sichuan, China (December 2016 to June 2019), we assessed baseline characteristics, vital signs, comorbidities, and prescriptions. LAR demonstrated a linear correlation with 3‐month readmission risk (HR = 1.60, 95% CI: 1.19–2.16). Tertile 3 (≥−0.48) exhibited higher risk than tertile 1 (<−0.83) and tertile 2 [−0.83, −0.48), with HRs and 95% CI of 1.49 (1.06–2.10), 1.43 (1.01–2.02), 1.48 (1.03–2.12), respectively. Subgroup and sensitivity analyses affirmed consistent influence of LAR on 3‐month readmission risk for HF.ConclusionsHigher LAR significantly correlates with increased 3‐month readmission risk in Chinese adult patients with HF, suggesting LAR is a valuable predictor for early readmission.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

Publisher

Wiley

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