The PhenX Toolkit: Recommended Measurement Protocols for Social Determinants of Health Research

Author:

Ives Cataia L.1,Krzyzanowski Michelle C.1ORCID,Marshall Vanessa J.2ORCID,Norris Keith3,Cockburn Myles4,Bentley‐Edwards Keisha5,Mohottige Dinushika6,Pollack Porter Keshia M.7,Dillard Denise8,Eisenberg Yochai9,Jiménez Monik C.10,Pérez‐Stable Eliseo J.2,Jones Nancy L.2,Dayal Jyoti11,Maiese Deborah R.112,Williams David1ORCID,Hendershot Tabitha P.1,Hamilton Carol M.1

Affiliation:

1. RTI International Research Triangle Park North Carolina

2. National Institute on Minority Health and Health Disparities National Institutes of Health Bethesda Maryland

3. Department of Medicine University of California Los Angeles California

4. Department of Dermatology and Department of Population & Public Health Sciences University of Southern California Los Angeles California

5. Division of General Internal Medicine, School of Medicine Duke University Durham North Carolina

6. Institute of Health Equity Research and Division of Nephrology Icahn School of Medicine at Mount Sinai New York New York

7. Department of Health Policy and Management Johns Hopkins Bloomberg School of Public Health Baltimore Maryland

8. Washington State University Seattle Washington

9. Department of Disability and Human Development University of Illinois at Chicago Chicago Illinois

10. Division of Women's Health, Department of Medicine, Harvard Medical School Brigham and Women's Hospital Boston Massachusetts

11. National Human Genome Research Institute National Institutes of Health Bethesda Maryland

12. Retired consultant

Abstract

AbstractHealth disparities are driven by unequal conditions in the environments in which people are born, live, learn, work, play, worship, and age, commonly termed the Social Determinants of Health (SDoH). The availability of recommended measurement protocols for SDoH will enable investigators to consistently collect data for SDoH constructs. The PhenX (consensus measures for Phenotypes and eXposures) Toolkit is a web‐based catalog of recommended measurement protocols for use in research studies with human participants. Using standard protocols from the PhenX Toolkit makes it easier to compare and combine studies, potentially increasing the impact of individual studies, and aids in comparability across literature. In 2018, the National Institute on Minority Health and Health Disparities provided support for an initial expert Working Group to identify and recommend established SDoH protocols for inclusion in the PhenX Toolkit. In 2022, a second expert Working Group was convened to build on the work of the first SDoH Working Group and address gaps in the SDoH Toolkit Collections. The SDoH Collections consist of a Core Collection and Individual and Structural Specialty Collections. This article describes a Basic Protocol for using the PhenX Toolkit to select and implement SDoH measurement protocols for use in research studies. © 2024 The Authors. Current Protocols published by Wiley Periodicals LLC. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.Basic Protocol: Using the PhenX Toolkit to select and implement SDoH protocols

Publisher

Wiley

Reference46 articles.

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4. Poverty, Racism, and the Public Health Crisis in America

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