Clinical practice for unspecified anxiety disorder in primary care

Author:

Sakurai Hitoshi1ORCID,Takeshima Masahiro2,Inada Ken3,Aoki Yumi4,Ie Kenya56,Kise Morito7,Yoshida Eriko8,Tsuboi Takashi1,Yamada Hisashi9,Hori Hikaru10,Inada Yasushi11,Shimizu Eiji1213,Mishima Kazuo2,Watanabe Koichiro1,Takaesu Yoshikazu114

Affiliation:

1. Department of Neuropsychiatry Kyorin University Faculty of Medicine Tokyo Japan

2. Department of Neuropsychiatry Akita University Graduate School of Medicine Akita Japan

3. Department of Psychiatry School of Medicine Kanagawa Japan

4. Department of Psychiatric and Mental Health Nursing St. Luke's International University Tokyo Japan

5. Department of Internal Medicine Division of General Internal Medicine Kanagawa Japan

6. Department of Internal Medicine, Division of General Internal Medicine Kawasaki Municipal Tama Hospital Kanagawa Japan

7. Centre for Family Medicine Development Japanese Health and Welfare Co‐Operative Federation Tokyo Japan

8. Department of General Internal Medicine Kawasaki Kyodo Hospital, Kawasaki Health Cooperative Association Kanagawa Japan

9. Department of Neuropsychiatry Hyogo Medicial University Hyogo Japan

10. Department of Psychiatry, Faculty of Medicine Fukuoka University Fukuoka Japan

11. Medical Corporation YUJIN‐KAI Inada Clinic Osaka Japan

12. Research Center for Child Mental Development Chiba University Chiba Japan

13. Department of Cognitive Behavioral Physiology Graduate School of Medicine Chiba Japan

14. Department of Neuropsychiatry Graduate School of Medicine Okinawa Japan

Abstract

AbstractAimClinicians face difficulties in making treatment decisions for unspecified anxiety disorder due to the absence of any treatment guidelines. The objective of this study was to investigate how familiar and how often primary care physicians use pharmacological and nonpharmacological approaches to manage the disorder.MethodsA survey was conducted among 117 primary care physicians in Japan who were asked to assess the familiarity of using each treatment option for unspecified anxiety disorder on a binary response scale (0 = “unfamiliar,” 1 = “familiar”) and the frequency on a nine‐point Likert scale (1 = “never used,” 9 = “frequently used”).ResultsWhile several benzodiazepine anxiolytics were familiar to primary care physicians, the frequencies of prescribing them, including alprazolam (4.6 ± 2.6), ethyl loflazepate (3.6 ± 2.4), and clotiazepam (3.5 ± 2.3), were low. In contrast, certain nonpharmacological options, including lifestyle changes (5.4 ± 2.3), coping strategies (5.1 ± 2.7), and psychoeducation for anxiety (5.1 ± 2.7), were more commonly utilized, but to a modest extent. When a benzodiazepine anxiolytic drug failed to be effective, primary care physicians selected the following management strategies to a relatively high degree: differential diagnosis (6.4 ± 2.4), referral to a specialist hospital (5.9 ± 2.5), lifestyle changes (5.2 ± 2.5), and switching to selective serotonin reuptake inhibitor (5.1 ± 2.4).ConclusionPrimary care physicians exercise caution when prescribing benzodiazepine anxiolytics for unspecified anxiety disorder. Nonpharmacological interventions and switching to SSRI are modestly employed as primary treatment options and alternatives to benzodiazepine anxiolytics. To ensure the safe and effective treatment of unspecified anxiety disorder in primary care, more information should be provided from field experts.

Publisher

Wiley

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