Chronic exposure to low doses of Pb induces hepatotoxicity at the physiological, biochemical, and transcriptomic levels of mice

Author:

Luo Ting1,Shen Manlu1,Zhou Jiajie1,Wang Xiaoyu1,Xia Jizhou1,Fu Zhengwei1ORCID,Jin Yuanxiang1ORCID

Affiliation:

1. Department of Biotechnology, College of Biotechnology and Bioengineering, Zhejiang University of Technology; Hangzhou China

Funder

National Natural Science Foundation of China

Zhejiang Provincial Natural Science Foundation of China

Publisher

Wiley

Subject

Health, Toxicology and Mutagenesis,Management, Monitoring, Policy and Law,Toxicology,General Medicine

Reference55 articles.

1. Low-dose arsenic compromises the immune response to influenza a infection in vivo;Kozul;Environ Health Persp,2009

2. Elevated lifetime lead exposure impedes osteoclast activity and produces an increase in bone mass in adolescent mice;Beier;Toxicol Sci,2016

3. The effect of low levels of lead (Pb) in the blood on levels of sphingosine-1-phosphate (S1P) and expression of S1P receptor 1 in the brain of the rat in the perinatal period;Lukomska;Chemosphere,2017

4. Active site-specific inhibition by 1,3-bis(2-chloroethyl)-1-nitrosourea of two genetically homologous flavoenzymes: glutathione reductase and lipoamide dehydrogenase;Ahmad;J Lab Clin Med,1985

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