Chemical constituents of <i>Panax ginseng</i> sprouts cultivated in Vietnam-Reference-Cited by-同舟云学术

Chemical constituents of Panax ginseng sprouts cultivated in Vietnam

Published:2024-02-26 Issue:2 Volume:62 Page:165-171
ISSN:2572-8288
Container-title:Vietnam Journal of Chemistry
language:en
Short-container-title:Vietnam Journal of Chemistry

Author:

Tuan Anh Hoang Le¹²,Duc Ngo Viet¹,Van Cong Pham¹,Van Hieu Ngo¹,Van Dan Nguyen¹,Trang Vu Thi¹,Hien Do Thi Thu¹,Tuan Do Thanh³,Anh Le Tuan⁴,Kim Jeong Ah⁵

Affiliation:

1. Center for Research and Technology Transfer Vietnam Academy of Science and Technology (VAST) Cau Giay Hanoi Vietnam

2. Department of Chemistry Graduate University of Science and Technology Hanoi Vietnam

3. Thai Binh University of Medicine and Pharmacy, Thai Binh Thai Binh Vietnam

4. Mientrung Institute for Scientific Research Vietnam National Museum of Nature, VAST, Huynh Thuc Khang Thua Thien Hue Vietnam

5. BK21 FOUR Community‐Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences Kyungpook National University Daegu Republic of Korea

Abstract

AbstractEight compounds, including 20(R)‐ginsenoside Rg3 (1), Ginsenoside Rd (2), ginsenosides Rg2 (3), ginsenosides Re (4), β‐sitosterol (5), daucosterol (6), stigmasterol (7), and stigmasterol‐3‐O‐β‐glucoside (8) were isolated from the Panax ginseng sprouts cultivated in Vietnam. Their structures were elucidated by 1H, 13C NMR, and MS spectroscopic techniques and compared with the previous publication. In addition, their inhibitory activity on NO production and cytotoxic effects against human embryonic kidney cells (HEK‐293A) and human hepatocellular carcinoma (HepG2) were evaluated. This is the first study of the phytochemical investigation of P. ginseng sprouts cultivated in Vietnam and ginseng sprouts also contained the same main active ginsenosides as in the 4–6‐year old roots.

Funder

Vietnam Academy of Science and Technology

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/vjch.202300181

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