Idiopathic basal ganglia calcification presenting with obsessive‐compulsive symptoms: A case report

Author:

Yoshioka Daisuke1ORCID,Yamanashi Takehiko1ORCID,Taneda Kenta2,Matsukawa Takashi3,Orimo Kenta3,Iwata Masaaki1

Affiliation:

1. Division of Neuropsychiatry, Faculty of Medicine Tottori University Yonago Japan

2. Division of Neurology, Faculty of Medicine Tottori University Yonago Japan

3. Department of Neurology, Graduate School of Medicine The University of Tokyo Tokyo Japan

Abstract

AbstractBackgroundIdiopathic basal ganglia calcification (IBGC), also known as Farh's disease, is a rare neurodegenerative disorder characterized by calcification of the basal ganglia and other brain regions. This disease usually occurs in middle‐aged patients and presents with various neurological and psychiatric symptoms. The exact prevalence is unknown; however, population genomic data analysis suggests a prevalence of at least 4.5/10,000 to 3.3/1000, indicating that the disease is more common than previously thought and remains underdiagnosed.Case PresentationWe report the case of a middle‐aged Japanese man who attempted suicide twice because of obsessive‐compulsive ideation caused by trivial triggers. The patient's psychiatric symptoms resolved relatively quickly after hospitalization, and imaging and genetic testing led to a diagnosis of IBGC.ConclusionThis case report illustrates the importance of including IBGC in the differential diagnosis of psychiatric symptoms that initially develop in middle‐aged patients.

Publisher

Wiley

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