Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor-Reference-Cited by-全球学者库

Concise Synthesis of Tunicamycin V and Discovery of a Cytostatic DPAGT1 Inhibitor

Published:2022-06-10 Issue:31 Volume:61 Page:
ISSN:1433-7851
Container-title:Angewandte Chemie International Edition
language:en
Short-container-title:Angew Chem Int Ed

Author:

Mitachi Katsuhiko¹^ORCID,Mingle David¹^ORCID,Effah Wendy²,Sánchez‐Ruiz Antonio³^ORCID,Hevener Kirk E.¹^ORCID,Narayanan Ramesh²^ORCID,Clemons William M.⁴,Sarabia Francisco⁵^ORCID,Kurosu Michio¹^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences College of Pharmacy University of Tennessee Health Science Center 881 Madison Avenue Memphis TN 38163 USA

2. Department of Medicine University of Tennessee Health Science Center 19 S. Manassas, Room 120 Memphis TN 38103 USA

3. Faculty of Pharmacy Campus de Albacete Universidad de Castilla-La Mancha Avda. Dr. José María Sánchez Ibáñez S/N 02008 Albacete Spain

4. Division of Chemistry and Chemical Engineering California Institute of Technology 1200 E. California Blvd. Pasadena CA 91125 USA

5. Department of Organic Chemistry Faculty of Sciences Universidad de Málaga, Campus de Teatinos 29071 Málaga Spain

Funder

National Institutes of Health

Publisher

Wiley

Subject

General Chemistry,Catalysis

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/anie.202203225

Reference104 articles.

2. Structure-based drug discovery by targeting N-glycan biosynthesis, dolichyl-phosphate N-acetylglucosaminephosphotransferase

3. Inhibition of N-Glycosylation towards Novel Anti-Cancer Chemotherapeutics

5. TUNICAMYCIN, A NEW ANTIBIOTIC. I

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1. The tunicamycin derivative TunR2 exhibits potent antibiotic properties with low toxicity in an in vivo Mycobacterium marinum-zebrafish TB infection model;The Journal of Antibiotics;2024-01-18

2. Precursor-Directed Biosynthesis and Biological Testing of omega-Alicyclic- and neo-Branched Tunicamycin N-Acyl Variants;ACS Chemical Biology;2023-10-03

3. Development of Novel DPAGT1 Inhibitors based on Tunicamycin V and its Homologous Structures;Journal of Synthetic Organic Chemistry, Japan;2023-03-01

4. An improved total synthesis of tunicamycin V;MethodsX;2023

5. Photo‐Induced Homologation of Carbonyl Compounds for Iterative Syntheses;Angewandte Chemie International Edition;2022-11-10