Brexpiprazole versus placebo or other antidepressive agents for treating depression

Author:

Ralovska Silviya1,Koychev Ivan2,Marinov Petar1,Furukawa Toshi A3,Mulsant Benoit45,Cipriani Andrea26

Affiliation:

1. Department of Neurology, Psychiatry, Physiotherapy and Rehabilitation, Preventive Medicine, and Public Health; Sofia University "St. Kliment Ohridski"; Sofia Bulgaria

2. Department of Psychiatry; University of Oxford; Oxford UK

3. Department of Health Promotion and Human Behavior; Kyoto University Graduate School of Medicine/School of Public Health; Kyoto Japan

4. Department of Psychiatry; Temerty Faculty of Medicine, University of Toronto; Toronto Canada

5. Centre for Addiction and Mental Health; Toronto Canada

6. Oxford Health NHS Foundation Trust; Oxford UK

Publisher

Wiley

Subject

Pharmacology (medical)

Reference116 articles.

1. Interventional, randomised, double-blind, parallel-group, placebo-controlled, flexible-dose long-term study to evaluate the maintenance of efficacy and safety of 1 to 3 mg/day of brexpiprazole as adjunctive treatment in patients with major depressive disorder with an inadequate response to antidepressant treatment (ADT) www.clinicaltrialsregister.eu/ctr-search/trial/2012-001380-76/results

2. A randomised, placebo-controlled 24-week study evaluating adjunctive brexpiprazole inpatients with major depressive disorder;Bauer;Acta Neuropsychiatrica,2019

3. Brexpiprazole as adjunctive treatment in patients with major depressive disorder with an inadequate response to antidepressant treatment clinicaltrials.gov/ct2/show/study/NCT01838681

4. A phase 3, multicenter, randomized, double-blind, placebo- and active comparator-controlled trial of flexible-dose brexpiprazole (OPC-34712) as adjunctive therapy in the treatment of adults with major depressive disorder, the Delphinus trial www.clinicaltrialsregister.eu/ctr-search/trial/2012-003948-67/results

5. Efficacy and safety of flexibly dosed brexpiprazole for the adjunctive treatment of major depressive disorder: a randomized, active-referenced, placebo-controlled study;Hobart;Current Medical Research and Opinion,2018

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