Integrative Functional Genomics Identifies Systemic Lupus Erythematosus Causal Genetic Variant in the IRF5 Risk Locus

Author:

Hou Guojun1,Zhou Tian2,Xu Ning2,Yin Zhihua3,Zhu Xinyi2,Zhang Yutong2,Cui Yange4,Ma Jianyang2,Tang Yuanjia2,Cheng Zhaorui2,Shen Yiwei2ORCID,Chen Yashuo3,Zou Ling‐Hua3,Wang Yong‐fei5ORCID,Yin Zihang6,Guo Ya6,Ding Huihua2ORCID,Ye Zhizhong3,Shen Nan7ORCID

Affiliation:

1. Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, China, and State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China

2. Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine Shanghai China

3. Shenzhen Futian Hospital for Rheumatic Diseases, and Joint Research Laboratory for Rheumatology of Shenzhen University Health Science Center and Shenzhen Futian Hospital for Rheumatic Diseases Shenzhen China

4. Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences Shanghai China

5. School of Life and Health Sciences, School of Medicine, and Warshel Institute for Computational Biology, The Chinese University of Hong Kong Shenzhen Guangdong China

6. Sheng Yushou Center of Cell Biology and Immunology, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University Shanghai China

7. Shanghai Institute of Rheumatology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Shenzhen Futian Hospital for Rheumatic Diseases, Shenzhen, China, State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China, Center for Autoimmune Genomics and Etiology, Division of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, and Department of...

Funder

National Natural Science Foundation of China

Sanming Project of Medicine in Shenzhen

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

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