ALDH1A1‐related stemness in high‐grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR‐PI3K/aurora kinase inhibitors

Author:

Kaipio Katja1ORCID,Chen Ping2,Roering Pia1,Huhtinen Kaisa1,Mikkonen Piia3,Östling Päivi45,Lehtinen Laura1,Mansuri Naziha1,Korpela Taina1,Potdar Swapnil6,Hynninen Johanna7,Auranen Annika8,Grénman Seija7,Wennerberg Krister69,Hautaniemi Sampsa10ORCID,Carpén Olli110ORCID

Affiliation:

1. Research Center for Cancer, Infections and Immunity, Institute of Biomedicine University of Turku Turku Finland

2. Integrated Cardio Metabolic Centre (ICMC), Department of Medicine Karolinska Institutet Huddinge Sweden

3. Institute for Molecular Medicine Finland, HiLIFE University of Helsinki Helsinki Finland

4. Science for Life Laboratory Department of Oncology & Pathology Karolinska Institutet Huddinge Sweden

5. Institute for Molecular Medicine Finland, FIMM University of Helsinki Helsinki Finland

6. Institute for Molecular Medicine Finland, High Throughput Biomedicine Unit (HTB) University of Helsinki Helsinki Finland

7. Department of Obstetrics and Gynaecology University of Turku and Turku University Hospital Turku Finland

8. Department of Obstetrics and Gynaecology University of Tampere and Tampere University Hospital Tampere Finland

9. Biotech Research & Innovation Centre (BRIC) University of Copenhagen Copenhagen Denmark

10. Research Programs Unit, Genome‐Scale Biology and Medicum, Faculty of Medicine University of Helsinki Helsinki Finland

Funder

Academy of Finland

Publisher

Wiley

Subject

Pathology and Forensic Medicine

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