Fas signaling induces stemness properties in colorectal cancer by regulation of Bmi1

Author:

Chen Jiaxuan1,Wang Yadong1,Zhuo Linghao1,Liu Zhizhong2,Liu Tao1,Li Wenjing1,Cai Yidong3,Zheng Haoxuan1ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology; Nanfang Hospital, Southern Medical University; Guangzhou China

2. Department of Gastroenterology; Affiliated Zhuhai Hospital, Southern Medical University (Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine); Zhuhai China

3. Department of Gastroenterology; Xiyuan Hospital, China Academy of Chinese Medical Sciences; Beijing China

Funder

Nanfang Hospital High Level Research Matching Funds

Pearl River S&T Nova Program of Guangzhou, China

The Training Plan of Excellent Young Teachers in Colleges and Universities of Guangdong Province, China

Special Support Program of High Level Talents Cultivation in Guangdong Province, China

National Natural Science Foundation of China

Guangzhou Pilot Project of Clinical and Translational Research Center

Guangdong Provincial Bio-engineering Research Center for Gastroenterology Diseases

China Alliance of Inflammatory Bowel Diseases, Wu Jie Ping Medical Foundation

Publisher

Wiley

Subject

Cancer Research,Molecular Biology

Reference33 articles.

1. Live and let die: regulatory mechanisms in Fas-mediated apoptosis;Curtin;Cell Signal,2003

2. Fas drives cell cycle progression in glioma cells via extracellular signalregulated kinase activation;Shinohara;Cancer Res,2000

3. Fas (CD95) induces proinflammatory cytokine responses by human monocytes and monocyte-derived macrophages;Park;J Immunol,2003

4. Fas-induced expression of chemokines in human glioma cells: involvement of extracellular signal-regulated kinase1/2 and p38 mitogen- activated protein kinase;Choi;Cancer Res,2001

5. CD95 promotes tumor growth;Chen;Nature,2010

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