Pharmacologic Repression of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γ Is Therapeutic in the Collagen-Induced Arthritis Experimental Model

Author:

Chang Mi Ra1,Lyda Brent1,Kamenecka Theodore M.1,Griffin Patrick R.1

Affiliation:

1. The Scripps Research Institute; Scripps Florida Jupiter

Publisher

Wiley

Subject

Immunology,Rheumatology,Immunology and Allergy

Reference62 articles.

1. Validity and reliability of the twenty-eight-joint count for the assessment of rheumatoid arthritis activity;Smolen;Arthritis Rheum,1995

2. Liver X receptor agonist prevents the evolution of collagen-induced arthritis in mice;Park;Rheumatology (Oxford),2010

3. Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts;Dayer;J Exp Med,1985

4. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors;Bertolini;Nature,1986

5. IL-1α/β blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-α blockade only ameliorates joint inflammation;Joosten;J Immunol,1999

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