Pharmacologic Repression of Retinoic Acid Receptor-Related Orphan Nuclear Receptor γ Is Therapeutic in the Collagen-Induced Arthritis Experimental Model
Author:
Affiliation:
1. The Scripps Research Institute; Scripps Florida Jupiter
Publisher
Wiley
Subject
Immunology,Rheumatology,Immunology and Allergy
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/art.38272/fullpdf
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3. Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts;Dayer;J Exp Med,1985
4. Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors;Bertolini;Nature,1986
5. IL-1α/β blockade prevents cartilage and bone destruction in murine type II collagen-induced arthritis, whereas TNF-α blockade only ameliorates joint inflammation;Joosten;J Immunol,1999
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