Correlative Light-Electron Microscopy Shows RGD-Targeted ZnO Nanoparticles Dissolve in the Intracellular Environment of Triple Negative Breast Cancer Cells and Cause Apoptosis with Intratumor Heterogeneity

Author:

Othman Basmah A.1,Greenwood Christina2,Abuelela Ayman F.3,Bharath Anil A.4,Chen Shu1,Theodorou Ioannis1,Douglas Trevor5,Uchida Maskai5,Ryan Mary1,Merzaban Jasmeen S.3,Porter Alexandra E.16

Affiliation:

1. Department of Materials; Imperial College London; Royal School of Mines; Exhibition Road London SW7 2AZ UK

2. Cell and Molecular Biology Research Laboratory; Faculty of Medical Sciences; Post Graduate Medical Institute; Anglia Ruskin University; Bishop Hall Lane; Chelmsford CM1 1SQ UK

3. Cell Migration and Signaling Laboratory; Division of Biological and Environmental Sciences and Engineering; King Abdullah University of Science and Engineering (KAUST); Thuwal 23955-6900 Saudi Arabia

4. Department of Bioengineering; Imperial College London; Royal School of Mines; Exhibition Road London SW7 2AZ UK

5. Department of Chemistry; Indiana University; 800 E. Kirkwood Avenue Bloomington IN 47405 USA

6. Imperial College London and London Centre for Nanotechnology; London SW7 2AZ UK

Funder

King Abdullah University of Science and Technology Faculty

Global Collaborative Research

Individual ERC

Publisher

Wiley

Subject

Pharmaceutical Science,Biomedical Engineering,Biomaterials

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