Inhibition of atypical protein kinase Cι induces apoptosis through autophagic degradation of β-catenin in esophageal cancer cells
Author:
Affiliation:
1. State Key Laboratory of Molecular Oncology; Cancer Institute (Hospital); Peking Union Medical College and Chinese Academy of Medical Sciences; Beijing China
2. Department of Histology and Embryology; Anhui Medical University; Hefei China
Funder
Specialized Research Fund for the Doctoral Program of Higher Education of China
National Science Fund
Chinese Hi-Tech R&D Program
Publisher
Wiley
Subject
Cancer Research,Molecular Biology
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/mc.22003/fullpdf
Reference53 articles.
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2. Atypical protein kinase Ciota plays a critical role in human lung cancer cell growth and tumorigenicity;Regala;J Biol Chem,2005
3. Atypical PKCiota contributes to poor prognosis through loss of apical-basal polarity and cyclin E overexpression in ovarian cancer;Eder;Proc Natl Acad Sci USA,2005
4. High expression of atypical protein kinase C lambda/iota in gastric cancer as a prognostic factor for recurrence;Takagawa;Ann Surg Oncol,2010
5. Protein kinase Ciota is required for Ras transformation and colon carcinogenesis in vivo;Murray;J Cell Biol,2004
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