Author:
Law Say‐Jong,Miller Thomas,Piran Uri,Klukas Carol,Chang Steve,Unger John
Abstract
AbstractA new series of stable acridinium ester conjugates have been developed for use as non‐isotopic labels in immunoassay. They have proved to be a flexible alternative to radioimmunoassay. We present data showing the successful development of immunoassays in sandwich, competitive and receptor formats. In addition, hydrophilic acridinium ester analogues have been synthesized, encapsulated in liposomes, and utilized as labels in immunoassay. The potential of this technology is discussed.
Reference19 articles.
1. Isolation of vitamin B12‐binding proteins using affinity chromatography;Allen R. H.;J. Biol. Chem.,1972
2. Diffusion of univalent ions across the lamellae of swollen phospholipids
3. Monoclonal antibody covalently coupled to liposomes: Specific targeting to cells
4. Davis P. J. (1979). Processes and materials for detecting and determining proteinaceous specific binding agents and materials bindable thereto. Patent: PCT International WO 8001515.
5. BioMag – a new support for magnetic affinity chromatography;Groman E. V.;Biotechniques,1985
Cited by
47 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献