Siglec-15 Regulates Osteoclast Differentiation by Modulating RANKL-Induced Phosphatidylinositol 3-Kinase/Akt and Erk Pathways in Association With Signaling Adaptor DAP12-Reference-Cited by-同舟云学术

Siglec-15 Regulates Osteoclast Differentiation by Modulating RANKL-Induced Phosphatidylinositol 3-Kinase/Akt and Erk Pathways in Association With Signaling Adaptor DAP12

Published:2013-11-19 Issue:12 Volume:28 Page:2463-2475
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Kameda Yusuke¹,Takahata Masahiko¹,Komatsu Miki¹,Mikuni Shintaro²,Hatakeyama Shigetsugu³,Shimizu Tomohiro¹,Angata Takashi⁴,Kinjo Masataka²,Minami Akio¹,Iwasaki Norimasa¹

Affiliation:

1. Department of Orthopedic Surgery; School of Medicine; Hokkaido University; Sapporo Japan

2. Laboratory of Molecular Cell Dynamics; Faculty of Advanced Life Science; Hokkaido University; Sapporo Japan

3. Department of Biochemistry; School of Medicine; Hokkaido University; Sapporo Japan

4. Glycan Recognition Team; Systems Glycobiology Research Group; RIKEN Advanced Science Institute; Wako Saitama Japan

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/jbmr.1989/fullpdf

Reference38 articles.

1. The signaling adapter protein DAP12 regulates multinucleation during osteoclast development;Humphrey;J Bone Miner Res.,2004

2. Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice;Kaifu;J Clin Invest.,2003

3. Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis;Koga;Nature.,2004

4. The immunomodulatory adapter proteins DAP12 and Fc receptor gamma-chain (FcRgamma) regulate development of functional osteoclasts through the Syk tyrosine kinase;Mocsai;Proc Natl Acad Sci USA.,2004

5. Cytoskeletal dysfunction dominates in DAP12-deficient osteoclasts;Zou;J Cell Sci.,2010

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