Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study-Reference-Cited by-同舟云学术

Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study

Published:2022-05-04 Issue:1 Volume:112 Page:62-68
ISSN:0009-9236
Container-title:Clinical Pharmacology & Therapeutics
language:en
Short-container-title:Clin Pharma and Therapeutics

Author:

de With Mirjam¹²,Knikman Jonathan³,de Man Femke M.¹,Lunenburg Carin A. T. C.⁴,Henricks Linda M.³⁵⁶,van Kuilenburg André B. P.⁷,Maring Jan G.⁸⁹,van Staveren Maurice C.¹⁰,de Vries Niels¹¹,Rosing Hilde¹¹,Beijnen Jos H.¹¹¹²,Pluim Dick³,Modak Anil¹³,Imholz Alex L. T.¹⁴,van Schaik Ron H. N.²,Schellens Jan H. M.¹²,Gelderblom Hans⁴,Cats Annemieke¹⁵,Guchelaar Henk‐Jan¹⁶¹⁷,Mathijssen Ron H. J.¹,Swen Jesse J.¹⁶¹⁷,Meulendijks Didier³⁵¹⁸

Affiliation:

1. Department of Medical Oncology Erasmus Medical Center Cancer Institute Rotterdam The Netherlands

2. Department of Clinical Chemistry Erasmus Medical Center Rotterdam The Netherlands

3. Division of Pharmacology The Netherlands Cancer Institute Amsterdam The Netherlands

4. Department of Medical Oncology Leiden University Medical Center Leiden The Netherlands

5. Division of Medical Oncology Department of Clinical Pharmacology The Netherlands Cancer Institute Amsterdam The Netherlands

6. Department of Clinical Chemistry and Laboratory Medicine Leiden University Medical Center Leiden The Netherlands

7. Laboratory Genetic Metabolic Diseases Department of Clinical Chemistry Amsterdam UMC Cancer Center Amsterdam Amsterdam Gastroenterology Endocrinology Metabolism University of Amsterdam Amsterdam The Netherlands

8. Department of Pharmacy Isala Hospital Zwolle The Netherlands

9. Isala Diaconessen Hospital Meppel The Netherlands

10. Department of Clinical Pharmacy and Toxicology Treant HealthgroupScheper Hospital Emmen The Netherlands

11. Department of Pharmacy & Pharmacology The Netherlands Cancer Institute Amsterdam The Netherlands

12. Division of Pharmacoepidemiology and Clinical Pharmacology Department of Pharmaceutical Sciences Faculty of Science Utrecht University Utrecht The Netherlands

13. Cambridge Isotope Laboratories Tewksbury Massachusetts USA

14. Department of Internal Medicine Deventer Hospital Deventer The Netherlands

15. Division of Medical Oncology Department of Gastrointestinal Oncology The Netherlands Cancer Institute Amsterdam The Netherlands

16. Department of Clinical Pharmacy and Toxicology Leiden University Medical Center Leiden The Netherlands

17. Leiden Network for Personalised Therapeutics (LNPT) Leiden The Netherlands

18. Late Development Oncology AstraZeneca Cambridge UK

Funder

KWF Kankerbestrijding

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology