Sentinel node identification in laryngeal and pharyngeal carcinoma after flexible endoscopy‐guided tracer injection under topical anesthesia: A feasibility study-Reference-Cited by-同舟云学术

Sentinel node identification in laryngeal and pharyngeal carcinoma after flexible endoscopy‐guided tracer injection under topical anesthesia: A feasibility study

Published:2023-03-21 Issue:6 Volume:45 Page:1359-1366
ISSN:1043-3074
Container-title:Head & Neck
language:en
Short-container-title:Head & Neck

Author:

Driessen Daphne A. J. J.¹^ORCID,Arens Anne I. J.²,Dijkema Tim¹,Weijs Willem L. J.³,Draaijer Lisette C.⁴,van den Broek Guido B.⁴,Takes Robert P.⁴^ORCID,Honings Jimmie⁴^ORCID,Kaanders Johannes H. A. M.¹

Affiliation:

1. Department of Radiation Oncology Radboud University Medical Center Nijmegen the Netherlands

2. Department of Medical Imaging Radboud University Medical Center Nijmegen the Netherlands

3. Department of Oral‐ and Maxillofacial Surgery and Head and Neck Surgery Radboud University Medical Center Nijmegen the Netherlands

4. Department of Otorhinolaryngology – Head and Neck Surgery Radboud University Medical Center Nijmegen the Netherlands

Abstract

AbstractBackgroundThe aim of this study was to investigate the feasibility of flexible endoscopy‐guided tracer injection for sentinel lymph node (SLN) identification in patients with laryngeal and pharyngeal carcinoma.MethodsSixteen cT1‐4N0‐2M0 patients with laryngeal or pharyngeal carcinoma underwent intra‐ and peritumoral [99mTc]Tc‐nanocolloid injections after topical anesthesia under endoscopic guidance. SPECT–CT scans were performed at two time points.ResultsTracer injection and visualization of SLNs was successful in 15/16 (94%) patients. Median number of tracer injections was 1 intratumoral and 3 peritumoral. The median duration of the endoscopic procedure including tracer injection after biopsy taking was 7 min (range 4–16 min). A total of 28 SLNs were identified which were all visualized on the early and late SPECT–CT. Most SLNs were visualized in neck levels II and III.ConclusionsFlexible endoscopy‐guided tracer injection for SLN identification is a feasible and fast procedure in laryngeal and pharyngeal carcinoma patients.

Publisher

Wiley

Subject

Otorhinolaryngology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hed.27347

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