Three New Steriodal Saponins from the Rhizomes of Tupistra chinensis Baker
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Published:2023-03
Issue:3
Volume:20
Page:
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ISSN:1612-1872
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Container-title:Chemistry & Biodiversity
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language:en
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Short-container-title:Chemistry & Biodiversity
Author:
He Xuefeng12,
Yuan Xiaofeng2,
Liu Yang2,
Qiu Pengcheng2,
Bi Linlin2,
Tang Haifeng2,
Lu Yunyang2
Affiliation:
1. Health Services Planning Section Department of Medical Service, General Hospital of Northern Theater Command Shenyang 110016 China
2. Department of Chinese Materia Medica and Natural Medicines School of Pharmacy Air Force Medical University Xi'an 710032 China
Abstract
AbstractThe phytochemical constituent investigation on the 70 % ethanol extract of the rhizomes of Tupistra chinensis Baker resulted in the isolation of three new steroidal saponins which were named tuchinosides A–C (1–3). Their structures were determined by extensive spectrum analysis and chemical evidence, especially 2D NMR and HR‐ESI‐MS techniques. In addition, the cytotoxicity of compounds 1–3 against several human cancer cell lines was evaluated.
Funder
National Natural Science Foundation of China
Natural Science Basic Research Program of Shaanxi Province
Subject
Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering
Reference28 articles.
1. S. Liang M. N. Tamura.’Flora of China’ Science Press Beijing 2000 Vol. 24 p. 235–239.
2. ‘Research review in the main chemical constituents and pharmacological effects of Tupistra chinensis Bak.’;Liu S.;Asian J. Tradit. Med.,2016
3. ‘Research Progress on Chemical Constituents and Pharmacological Activities of Tupistra chinensis Baker’;Wu G.;Chin. Wild Plant Resour.,2020
4. Steroidal Saponins from the Roots and Rhizomes of Tupistra chinensis
5. A cytotoxic cardenolide and a saponin from the rhizomes of Tupistra chinensis