Structural Diversity, Spectral Data, and Pharmacological Effects of Genus Nigella

Author:

Luan Nguyen Thanh1ORCID,Anam Aqsa2ORCID,Hofdey Megbes Farah3,Mourad Mohammed Ibrahim4,Abed Ahmed S.5,Imran Mallhi Ali6ORCID,Abdullateef Alzubaidi Mazin7,Ali Amir Ahmed8,Ayub Asif2ORCID,Arshad Muhammad2ORCID,Rauf Abdul2ORCID,Ha Pham Thi Hai9

Affiliation:

1. Department of Science and Technology HUTECH University 475 A Dien Bien Phu Street, Ward 25 Binh Thanh District, Ho Chi Minh City 700000 Vietnam

2. Institute of Chemistry The Islamia University of Bahawalpur Bahawalpur 63100 Pakistan

3. Nursing Department Al-Mustaqbal University College 5001 Babylon Iraq

4. Department of medical Laboratories AL-Nisour University College 10064 Baghdad Iraq

5. Department of Prosthetic Dental Technology Hilla University college 5001 Babylon Iraq

6. Department of Chemistry Government College University Faisalabad Punjab 38000 Pakistan

7. Department of Anesthesia Al-Mustaqbal University college 5001 Babylon Iraq

8. Department of Medical Laboratories Technology AL-Nisour University College 10064 Baghdad Iraq

9. NTT Hi-Tech Institute Nguyen Tat Thanh University 298-300 A Nguyen Tat Thanh Street Ward 13, District 4, Ho Chi Minh City 700000 Vietnam

Abstract

AbstractNigella is one of the most studied plants because of its pharmacological properties like anti‐parasitic, anti‐inflammatory, neuro‐protective, hepatoprotective, and anti‐cancerous. In this study, about 20 species of the genus Nigella were reviewed and among them, N. damascene, N. glandulifera, and N. sativa are widely studied for their phytochemical and pharmacological effects. This review describes the phytochemical composition of the genus Nigella, which constitutes many of the compounds including alkaloids, flavonoids, saponins, and terpenoids. The extracts produced by using different solvents and the isolated compounds displayed a wide range of biological activity. These compounds were identified by different spectral techniques. The spectral detail of some advanced techniques including EIS‐MS, UV/VIS, IR, 13C‐NMR, and 1H‐NMR of some important phytoconstituents of Nigella spp. has been compiled for the first time in this review which will be helpful to explore and further investigate the chemical composition of this genus.

Publisher

Wiley

Subject

Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering

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