Affiliation:
1. Department of Chemistry CHRIST (Deemed to be University) Bangalore Karnataka) 560029 India
2. Institute for Water and Wastewater Technology Durban University of Technology Durban 4000 South Africa
3. Department of Biomedical and Clinical Technology Durban University of Technology Durban 4000 South Africa
Abstract
AbstractFused coumarins, because of their remarkable biological and therapeutic properties, particularly pyranocoumarins, have caught the interest of synthetic organic chemists, leading to the development of more efficient and environmentally friendly protocols for synthesizing pyranocoumarin derivatives. These compounds are the most promising heterocycles discovered in both natural and synthetic sources, with anti‐inflammatory, anti‐HIV, antitubercular, antihyperglycemic, and antibacterial properties. This review employed the leading scientific databases Scopus, Web of Science, Google Scholar, and PubMed up to the end of 2022, as well as the combining terms pyranocoumarins, synthesis, isolation, structural elucidation, and biological activity. Among the catalysts employed, acidic magnetic nanocatalysts, transition metal catalysts, and carbon‐based catalysts have all demonstrated improved reaction yields and facilitated reactions under milder conditions. Herein, the present review discusses the various multicomponent synthetic strategies for pyranocoumarins catalyzed by transition metal‐based catalysts, transition metal‐based nanocatalysts, transition metal‐free catalysts, carbon‐based nanocatalysts, and their potential pharmacological activities.
Funder
Durban University of Technology
Subject
Molecular Biology,Molecular Medicine,General Chemistry,Biochemistry,General Medicine,Bioengineering
Cited by
1 articles.
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