Affiliation:
1. Department of Medicine Dow University of Health Sciences Karachi Pakistan
2. Dow University of Health Sciences Karachi Pakistan
3. Department of Medicine Kabul Medical University Kabul Afghanistan
Abstract
Key Clinical MessageThis study paper's main goal is to report rare cases of skull base meningiomas that exemplify the complexities of diagnosis, therapy, and postoperative care. By describing these rare cases, we hope to advance knowledge of the clinical signs, difficulties, and prognoses of skull base meningiomas in a challenging anatomical setting. In the posterior cranial fossa, our investigation reveals a unique example of skull base meningioma that involved numerous cranial nerves and complex vasculature. A variety of visual abnormalities were present in the patient's clinical presentations, highlighting the wide range of symptoms that these tumors might cause depending on their precise positions. These cases highlight the critical importance of preoperative imaging, including high‐resolution MRI and angiography, as well as the diagnostic difficulties these tumors pertain. By reporting these instances, our research adds to the body of knowledge about skull base meningiomas and offers insightful information about the nuances of their therapies. Our findings highlight the importance of individualized treatment plans, interdisciplinary cooperation, and the demand for continued study to better comprehend these convoluted tumors. Such studies are essential for advancing our knowledge of these enigmatic tumors, guiding clinical judgment, and eventually improving patient outcomes. These findings are important because they can fill information gaps, improve treatment plans, and encourage additional research in neuro‐oncology.AbstractThis study presents a series of three rare cases of skull base meningiomas, emphasizing the complexities in diagnosis, treatment, and postoperative care. The patients' clinical presentations and imaging highlighted the diverse symptoms and challenges associated with these tumors, found in intricate anatomical locations. The cases underscore the crucial role of preoperative high‐resolution imaging and angiography in diagnostic accuracy. Surgical intervention, guided by a multidisciplinary approach, is pivotal in managing these demanding cases. Histopathological examinations confirmed atypical meningiomas. The postoperative phases involved meticulous care to ensure optimal recovery and functional outcomes. Our findings contribute to the understanding of skull base meningiomas, emphasizing the need for personalized treatment plans and ongoing research to improve patient outcomes in neuro‐oncology.
Reference58 articles.
1. Meningioma of the Skull Base.https://stanfordhealthcare.org/medical‐conditions/brain‐and‐nerves/meningioma‐skull‐base.html#:~:text=A%20meningioma%20of%20the%20skull %2C%20nerves%2C%20or%20blood%20vessels
2. Incidence, clinico‐radiological features and outcome of skull base versus non‐skull base meningiomas treated in Kuala Lumpur general hospital: a five‐year experience;Kong CC;Malays J Med Sci,2018
3. Meningioma: Statistics.https://www.cancer.net/cancer‐types/meningioma/statistics#:~:text=treatment%20plan%20works.‐ The%205%2Dyear%20relative%20survival%20rate%20for%20malignant%20meningioma%20is survival%20rate%20is%20around%2065%25
4. Sex-specific aspects of epidemiology, molecular genetics and outcome: primary brain tumours
5. Meningiomas.https://www.aans.org/en/Patients/Neurosurgical‐Conditions‐and‐Treatments/Meningiomas#:~:text=Sophisticated%20imaging%20techniques%20can%20help tissue%20biopsies%20and%20tumor%20removal