Inhibition of the dopamine transporter promotes lysosome biogenesis and ameliorates Alzheimer's disease–like symptoms in mice

Author:

Yin Limin1,Zhou Jianhui23,Li Tianyou1,Wang Xinghua3,Xue Wenlong1,Zhang Jie1,Lin Lingxi1,Wang Ning1,Kang Xinyi1,Zhou Yu234ORCID,Liu Hong234ORCID,Li Yang1ORCID

Affiliation:

1. Department of Pharmacology State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Key Laboratory of Metabolism and Molecular Medicine, Ministry of Education School of Basic Medical Science Fudan University Shanghai China

2. State Key Laboratory of Drug Research Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai China

3. School of Chinese Materia Medica Nanjing University of Chinese Medicine Nanjing China

4. School of Pharmacy University of Chinese Academy of Sciences Beijing China

Funder

Ministry of Science and Technology of the People's Republic of China

National Natural Science Foundation of China

State Key Laboratory of Drug Research

China Postdoctoral Science Foundation

Publisher

Wiley

Subject

Psychiatry and Mental health,Cellular and Molecular Neuroscience,Geriatrics and Gerontology,Neurology (clinical),Developmental Neuroscience,Health Policy,Epidemiology

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