DEPTOR Prevents Osteoarthritis Development Via Interplay With TRC8 to Reduce Endoplasmic Reticulum Stress in Chondrocytes-Reference-Cited by-全球学者库

DEPTOR Prevents Osteoarthritis Development Via Interplay With TRC8 to Reduce Endoplasmic Reticulum Stress in Chondrocytes

Published:2020-09-24 Issue:2 Volume:36 Page:400-411
ISSN:0884-0431
Container-title:Journal of Bone and Mineral Research
language:en
Short-container-title:J Bone Miner Res

Author:

Li Kai¹²³^ORCID,Yang Panpan¹,Zhang Yuwei²,Zhang Yue²^ORCID,Cao He¹,Liu Peilin¹,Huang Bin¹,Xu Song⁴,Lai Pinglin¹,Lei Guanghua⁵,Liu Jia⁶,Tang Yujin⁶,Bai Xiaochun¹²³^ORCID,Zou Zhipeng²

Affiliation:

1. Academy of Orthopedics, Guangdong Province, Guangdong Provincial Key Laboratory of Bone and Joint Degeneration Diseases The Third Affiliated Hospital of Southern Medical University Guangzhou China

2. State Key Laboratory of Organ Failure Research, Department of Cell Biology School of Basic Medical Sciences, Southern Medical University Guangzhou China

3. Guangzhou Regenerative Medicine and Health Guangdong Laboratory Guangzhou China

4. Department of Orthopedics and Arthroplasty Nanfang Hospital, Southern Medical University Guangzhou China

5. Department of Orthopaedics Xiangya Hospital, Central South University Changsha China

6. Department of Orthopedics Affiliated Hospital of Youjiang Medical University for Nationalities Baise China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Orthopedics and Sports Medicine,Endocrinology, Diabetes and Metabolism

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbmr.4176

Reference36 articles.

1. Osteoarthritis

2. Osteoarthritis

3. Bone remodelling in osteoarthritis

4. Osteoarthritis: A disease of the joint as an organ

5. Chondrocyte death by apoptosis is associated with cartilage matrix degradation

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2. Autophagy and apoptosis: regulatory factors of chondrocyte phenotype transition in osteoarthritis;Human Cell;2023-06-05

3. Skeletal diseases caused by mutations in PTH1R show aberrant differentiation of skeletal progenitors due to dysregulation of DEPTOR;Frontiers in Cell and Developmental Biology;2023-01-16

4. The natural product salicin alleviates osteoarthritis progression by binding to IRE1α and inhibiting endoplasmic reticulum stress through the IRE1α-IκBα-p65 signaling pathway;Experimental & Molecular Medicine;2022-11-10

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