Targeting the PI 3K signaling pathway in KRAS mutant colon cancer

Author:

Hong Suntaek1,Kim SoYoung23,Kim Hye Youn1,Kang Myunghee4,Jang Ho Hee13,Lee Won‐Suk123

Affiliation:

1. Lee Gil Ya Cancer and Diabetes Institute Gachon University Incheon Korea

2. Department of Surgery Gil Medical Center Gachon University Incheon Korea

3. Gachon Medical Research Institute Gil Medical Center Incheon Korea

4. Department of Pathology Gil Medical Center Gachon University Incheon Korea

Funder

Gachon University

Publisher

Wiley

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology

Reference20 articles.

1. CALGB/SWOG 80405: Phase III trial of irinotecan/5‐FU/leucovorin (FOLFIRI) or oxaliplatin/5‐FU/leucovorin (mFOLFOX6) with bevacizumab (BV) or cetuximab (CET) for patients (pts) with KRAS wild‐type (wt) untreated metastatic adenocarcinoma of the colon or rectum (MCRC);Venook A. P.;ASCO Meet Abstr.,2014

2. Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway

3. Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

4. Cetuximab and Chemotherapy as Initial Treatment for Metastatic Colorectal Cancer

5. Fluorouracil, Leucovorin, and Oxaliplatin With and Without Cetuximab in the First-Line Treatment of Metastatic Colorectal Cancer

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