Synthesis of 9,9‐Disubstituted 9H‐Pyrrolo[1,2‐a]indoles by Hydriodic Acid‐Catalyzed Cyclization of 1‐[2‐(1‐Aryl(or methyl)ethenyl)phenyl]‐1H‐pyrroles-Reference-Cited by-同舟云学术

Synthesis of 9,9‐Disubstituted 9H‐Pyrrolo[1,2‐a]indoles by Hydriodic Acid‐Catalyzed Cyclization of 1‐[2‐(1‐Aryl(or methyl)ethenyl)phenyl]‐1H‐pyrroles

Published:2011-07 Issue:7 Volume:94 Page:1277-1282
ISSN:0018-019X
Container-title:Helvetica Chimica Acta
language:en
Short-container-title:Helvetica Chimica Acta

Author:

Kobayashi Kazuhiro,Hashimoto Kenichi,Hashimoto Hiroo,Kondo Hideaki,Konishi Hisatoshi

Abstract

AbstractA novel method is reported for the synthesis of 9,9‐disubstituted 9H‐pyrrolo[1,2‐a]indoles. Cyclization of 1‐[2‐(1‐aryl(or methyl)ethenyl)phenyl]‐1H‐pyrroles, which can be easily prepared from 2‐(1‐aryl(or methyl)ethenyl)anilines, proceeds smoothly, in general, at 0° in the presence of a catalytic (or an equimolar) amount of HI in MeCN to provide the desired products.

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/hlca.201100091

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