Dynamic crosstalk between hematopoietic stem cells and their niche from emergence to aging-Reference-Cited by-同舟云学术

Dynamic crosstalk between hematopoietic stem cells and their niche from emergence to aging

Published:2023-01-27 Issue:3 Volume:45 Page:
ISSN:0265-9247
Container-title:BioEssays
language:en
Short-container-title:BioEssays

Author:

Deng Zhao‐hua¹²^ORCID,Ma Lan‐yue¹²³,Chen Qi¹²^ORCID,Liu Yang⁴^ORCID

Affiliation:

1. Center for cell lineage and development CAS Key Laboratory of Regenerative Biology Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine GIBH‐HKU Guangdong‐Hong Kong Stem Cell and Regenerative Medicine Research Centre, GIBH‐CUHK Joint Research Laboratory on Stem Cell and Regenerative Medicine Guangzhou Institutes of Biomedicine and Health Chinese Academy of Sciences Guangzhou China

2. China‐New Zealand Joint Laboratory on Biomedicine and Health Guangzhou China

3. University of Chinese Academy of Sciences Beijing China

4. School of Medicine South China University of Technology Guangzhou China

Abstract

AbstractThe behavior of somatic stem cells is regulated by their niche. Interaction between hematopoietic stem cells (HSCs) and their niches are a representative model to understand stem cell‐niche interplay. Here, we provide an overview of crosstalk between HSCs and their niches in bone marrow and extramedullary organs following the life journey of HSCs from emergence, development, maturation until aging. We highlight the unique differences of HSC niches in different life stages within various organs focusing on recent literature to propose new speculations and hypotheses.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

South China University of Technology

Science and Technology Planning Project of Guangdong Province

Publisher

Wiley

Subject

General Biochemistry, Genetics and Molecular Biology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bies.202200121

Reference130 articles.

1. Dynamic niches in the origination and differentiation of haematopoietic stem cells

2. Hematopoietic Stem Cell Gene Therapy: Progress and Lessons Learned