Author:
Schultze-Lutter Frauke,Ruhrmann Stephan,Picker Heinz,Von Reventlow Heinrich Graf,Brockhaus-Dumke Anke,Klosterkötter Joachim
Abstract
BackgroundDepression is a frequent condition in early psychosis. Therefore, early
detection instruments should distinguish depression from beginning
psychosisAimsTo examine whether basic symptoms, i.e. subtle subjective deficits,
differ between participants suffering from a potential prodrome
(n = 146), first-episode schizophrenia
(n= 153) and non-psychotic depression
(n = 115)MethodBasic symptoms were assessed with the Schizophrenia Proneness
InstrumentResultsThe prodrome and schizophrenia groups did not differ in level of basic
symptoms but both had higher levels than the depression group. DSM – IV
depression was frequent in those suffering from a potential prodrome
(38%) and first-episode schizophrenia (21%). In both groups, participants
with and without depression did not differ in basic symptoms. In
multivariate analyses, consideration of current depression generally
facilitated correct group classification, except for participants
suffering from both a potential prodrome and depressionConclusionsCognitive basic symptoms distinguished well between all three groups.
However, identification of persons suffering from a potential prodrome
might be enhanced by considering current affective status
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference21 articles.
1. Transition to psychosis in Chinese high risk population;Lam;Schizophrenia Research,2004
2. Depression in first-episode schizophrenia;Koreen;American Journal of Psychiatry,1993
3. Diagnostic validity of basic symptoms
4. Early detection and intervention in the initial prodromal phase of schizophrenia;Ruhrmann;Pharmacopsychiatry,2003
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