Author:
Eapen V.,Pauls D. L.,Robertson M. M.
Abstract
Complex segregation analyses were performed on families ascertained through 40 unselected consecutive patients with Tourette's syndrome to examine the hypothesis that its transmission is consistent with genetic inheritance. Analyses were done using several diagnostic classifications. All results were consistent with an autosomal dominant gene with high penetrance. The penetrances ranged from 0.882 to 1.000 for males and 0.452 to 0.980 for females, depending upon the specific classification scheme incorporated into the analyses.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Reference22 articles.
1. The Inheritance of Gilles de la Tourette's Syndrome and Associated Behaviors
2. Detection of major gene for Gilles de la Tourette syndrome;Comings;American Journal of Human Genetics,1984
Cited by
170 articles.
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