Author:
Vonmoos Matthias,Hulka Lea M.,Preller Katrin H.,Jenni Daniela,Baumgartner Markus R.,Stohler Rudolf,Bolla Karen I.,Quednow Boris B.
Abstract
BackgroundDependent cocaine users consistently display cognitive deficits but cognitive performance of recreational cocaine users has rarely been investigated.AimsTo examine whether cognitive performance is impaired in relatively pure recreational and dependent cocaine users.MethodThe cognitive performance of recreational (n = 68) and dependent cocaine users (n = 30) was compared with the performance of stimulant-naive controls (n = 68) employing an extensive neuropsychological test battery. Moreover, the impact of attention-deficit hyperactivity disorder (ADHD) symptoms, craving and early age at onset was analysed.ResultsDependent cocaine users display broad cognitive impairments in the domains of attention, working memory, declarative memory and executive functions. The performance of recreational cocaine users in all four domains was intermediate between that of controls and dependent users and they displayed significant deficits foremost in the domains of attention and working memory. In addition, ADHD symptoms, craving and age at onset were important modulators of cognitive function in cocaine users.ConclusionsCognitive deficits occur at a recreational and non-dependent level of cocaine use. Cocaine use and ADHD seem to have mutually aggravating effects on cognitive impairment.
Publisher
Royal College of Psychiatrists
Subject
Psychiatry and Mental health
Cited by
141 articles.
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