Adjunctive fast repetitive transcranial magnetic stimulation in depression

Author:

Anderson Ian M.,Delvai Nicola A.,Ashim Bettadapura,Ashim Sindhu,Lewin Cherry,Singh Vineet,Sturman Daniel,Strickland Paul L.

Abstract

SummaryThe place of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression remains unclear. In this sham-controlled study we determined the efficacy and acceptability of fast, left frontal rTMS given three times a week over 4–6 weeks to 29 patients with depression (79% treatment-resistant). The procedure was generally well tolerated and more effective than sham treatment (55 v. 7% responding, P<0.05), with improvement maintained to 12 weeks. This therapy could be a useful addition to available treatments but further research is needed to determine the optimum treatment parameters.

Publisher

Royal College of Psychiatrists

Subject

Psychiatry and Mental health

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