Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected-Reference-Cited by-同舟云学术

Novel tau biomarkers phosphorylated at T181, T217 or T231 rise in the initial stages of the preclinical Alzheimer’s continuum when only subtle changes in Aβ pathology are detected

Published:2020-11-10 Issue:12 Volume:12 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Suárez‐Calvet Marc¹²³⁴^ORCID,Karikari Thomas K⁵,Ashton Nicholas J⁵⁶⁷⁸^ORCID,Lantero Rodríguez Juan⁵,Milà‐Alomà Marta¹²⁴⁹,Gispert Juan Domingo¹²⁹¹⁰,Salvadó Gemma¹²,Minguillon Carolina¹²⁴,Fauria Karine¹⁴,Shekari Mahnaz¹²⁹,Grau‐Rivera Oriol¹²³⁴,Arenaza‐Urquijo Eider M¹²⁴,Sala‐Vila Aleix¹²,Sánchez‐Benavides Gonzalo¹²⁴,González‐de‐Echávarri José Maria¹²,Kollmorgen Gwendlyn¹¹,Stoops Erik¹²,Vanmechelen Eugeen¹²,Zetterberg Henrik⁵¹³¹⁴¹⁵,Blennow Kaj⁵¹³^ORCID,Molinuevo José Luis¹²⁴⁹^ORCID,Beteta Annabella,Cacciaglia Raffaele,Cañas Alba,Deulofeu Carme,Cumplido Irene,Dominguez Ruth,Emilio Maria,Falcon Carles,Fuentes Sherezade,Hernandez Laura,Huesa Gema,Huguet Jordi,Marne Paula,Menchón Tania,Operto Grégory,Polo Albina,Pradas Sandra,Soteras Anna,Vilanova Marc,Vilor‐Tejedor Natalia,

Affiliation:

1. Barcelonaβeta Brain Research Center (BBRC) Pasqual Maragall Foundation Barcelona Spain

2. IMIM (Hospital del Mar Medical Research Institute) Barcelona Spain

3. Servei de Neurologia Hospital del Mar Barcelona Spain

4. Centro de Investigación Biomédica en Red de sFragilidad y Envejecimiento Saludable (CIBERFES) Madrid Spain

5. Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology The Sahlgrenska Academy University of Gothenburg Gothenburg Sweden

6. Department of Psychiatry and Neurochemistry Institute of Neuroscience and Physiology Wallenberg Centre for Molecular and Translational Medicine The Sahlgrenska Academy at the University of Gothenburg Gothenburg Sweden

7. Institute of Psychiatry, Psychology & Neuroscience King’s College LondonMaurice Wohl Clinical Neuroscience Institute London UK

8. NIHR Biomedical Research Centre for Mental Health & Biomedical Research Unit for Dementia at South London & Maudsley NHS Foundation London UK

9. Universitat Pompeu Fabra Barcelona Spain

10. Centro de Investigación Biomédica en Red Bioingeniería Biomateriales y Nanomedicina Madrid Spain

11. Roche Diagnostics GmbH Penzberg Germany

12. ADx NeuroSciences Ghent Belgium

13. Clinical Neurochemistry Laboratory Sahlgrenska University Hospital Mölndal Sweden

14. Department of Neurodegenerative Disease UCL Institute of Neurology London UK

15. UK Dementia Research Institute at UCL London UK

Funder

“la Caixa” Foundation

Alzheimer's Association

H2020 Marie Skłodowska-Curie Actions

BrightFocus Foundation

H2020 European Research Council

EU Joint Programme – Neurodegenerative Disease Research

Instituto de Salud Carlos III

Ministerio de Ciencia, Innovación y Universidades

Ministerio de Economía y Competitividad

Svenska Forskningsrådet Formas

Alzheimer's Drug Discovery Foundation

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202012921

Reference113 articles.

1. Comparison of amyloid PET measured in Centiloid units with neuropathological findings in Alzheimer’s disease

2. A Practical Guide to Immunoassay Method Validation

3. CSF Phosphorylated Tau Protein and Mild Cognitive Impairment: A Prospective Study

4. Influence of tau PET, amyloid PET, and hippocampal volume on cognition in Alzheimer disease

5. Specific tau phosphorylation sites correlate with severity of neuronal cytopathology in Alzheimer's disease

Cited by 188 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Temporal Profiles of P-Tau, T-Tau, and P-Tau:Tau Ratios in Cerebrospinal Fluid and Blood from Moderate-Severe Traumatic Brain Injury Patients and Relationship to 6–12 Month Global Outcomes;Journal of Neurotrauma;2024-02-01

2. Passive immunotherapy for Alzheimer's disease;Ageing Research Reviews;2024-02

3. A nonhuman primate model with Alzheimer’s disease-like pathology induced by hippocampal overexpression of human tau;Alzheimer's Research & Therapy;2024-01-27

4. Graphene as basis of biological sensors for determining markers of neurodegenerative dementia;Medical alphabet;2024-01-19

5. Multi-Omic Blood Biomarkers as Dynamic Risk Predictors in Late-Onset Alzheimer’s Disease;International Journal of Molecular Sciences;2024-01-19