Drug‐like sphingolipid SH‐BC‐893 opposes ceramide‐induced mitochondrial fission and corrects diet‐induced obesity-Reference-Cited by-同舟云学术

Drug‐like sphingolipid SH‐BC‐893 opposes ceramide‐induced mitochondrial fission and corrects diet‐induced obesity

Published:2021-07-07 Issue:8 Volume:13 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Jayashankar Vaishali¹,Selwan Elizabeth¹,Hancock Sarah E²,Verlande Amandine³,Goodson Maggie O³,Eckenstein Kazumi H¹,Milinkeviciute Giedre⁴,Hoover Brianna M⁵,Chen Bin⁶,Fleischman Angela G⁵,Cramer Karina S⁴,Hanessian Stephen⁶,Masri Selma³,Turner Nigel²,Edinger Aimee L¹^ORCID

Affiliation:

1. Department of Developmental and Cell Biology University of California Irvine Irvine CA USA

2. School of Medical Sciences University of New South Wales Sydney NSW Australia

3. Department of Biological Chemistry University of California Irvine Irvine CA USA

4. Department of Neurobiology and Behavior University of California Irvine Irvine CA USA

5. Division of Hematology/Oncology Department of Medicine University of California Irvine CA USA

6. Department of Chemistry Université de Montréal Montréal QC Canada

Funder

Foundation for the National Institutes of Health

National Health and Medical Research Council

National Cancer Institute

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202013086

Reference117 articles.

1. An Improved High-Throughput Lipid Extraction Method for the Analysis of Human Brain Lipids

2. Morbidity and mortality associated with obesity

3. High glucose–induced ROS activates TRPM2 to trigger lysosomal membrane permeabilization and Zn 2+ -mediated mitochondrial fission

4. The STEP 1 trial for weight loss: a step change in treating obesity?

5. Leptin resensitisation: a reversion of leptin-resistant states

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