Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma-Reference-Cited by-同舟云学术

Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma

Published:2019-11-28 Issue:1 Volume:12 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Han Mingzhi¹²,Wang Shuai¹^ORCID,Yang Ning¹,Wang Xu¹,Zhao Wenbo¹,Saed Halala Sdik²,Daubon Thomas³⁴,Huang Bin¹,Chen Anjing¹⁵,Li Gang¹,Miletic Hrvoje²⁶,Thorsen Frits²⁷^ORCID,Bjerkvig Rolf²⁸^ORCID,Li Xingang¹^ORCID,Wang Jian¹²^ORCID

Affiliation:

1. Shandong Key Laboratory of Brain Function Remodeling Department of Neurosurgery Qilu Hospital of Shandong University and Institute of Brain and Brain‐Inspired Science Shandong University Jinan China

2. Department of Biomedicine University of Bergen Bergen Norway

3. INSERM U1029 Institut Nationale de la Santé et de la Recherche Médicale Pessac France

4. University Bordeaux Pessac France

5. School of Medicine Shandong University Jinan China

6. Department of Pathology Haukeland University Hospital Bergen Norway

7. Department of Biomedicine The Molecular Imaging Center University of Bergen Bergen Norway

8. NorLux Neuro‐Oncology Laboratory Department of Oncology Luxembourg Institute of Health Luxembourg City Luxembourg

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shandong Province

China Postdoctoral Science Foundation

Kreftforeningen

Norges Forskningsråd

Haukeland Universitetssjukehus

Universitetet i Bergen

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201910924

Reference62 articles.

1. CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer

2. Cholesterol: An Achilles’ Heel for Glioblastoma?

3. Mapping of the Allosteric Site in Cholesterol Hydroxylase CYP46A1 for Efavirenz, a Drug That Stimulates Enzyme Activity

4. Efavirenz: What is known about the cellular mechanisms responsible for its adverse effects

5. Identification of 5α,6α-Epoxycholesterol as a Novel Modulator of Liver X Receptor Activity

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