A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis-Reference-Cited by-同舟云学术

A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis

Published:2022-02-17 Issue:3 Volume:14 Page:
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Zhu Lucía¹,Retana Diana¹,García‐Gómez Pedro¹^ORCID,Álvaro‐Espinosa Laura¹,Priego Neibla¹,Masmudi‐Martín Mariam¹,Yebra Natalia¹,Miarka Lauritz¹,Hernández‐Encinas Elena²,Blanco‐Aparicio Carmen²,Martínez Sonia²^ORCID,Sobrino Cecilia³,Ajenjo Nuria³,Artiga Maria‐Jesus³^ORCID,Ortega‐Paino Eva³,Torres‐Ruiz Raúl⁴⁵^ORCID,Rodríguez‐Perales Sandra⁴,Soffietti Riccardo⁶,Bertero Luca⁷^ORCID,Cassoni Paola⁷,Weiss Tobias⁸^ORCID,Muñoz Javier⁹^ORCID,Sepúlveda Juan Manuel¹⁰,González‐León Pedro¹¹,Jiménez‐Roldán Luis¹¹¹²¹³,Moreno Luis Miguel¹¹^ORCID,Esteban Olga¹¹,Pérez‐Núñez Ángel¹¹¹²¹⁴^ORCID,Hernández‐Laín Aurelio¹³,Toldos Oscar¹³,Ruano Yolanda¹⁵¹⁶,Alcázar Lucía¹⁷,Blasco Guillermo¹⁷,Fernández‐Alén José¹⁷,Caleiras Eduardo¹⁸,Lafarga Miguel¹⁹^ORCID,Megías Diego²⁰,Graña‐Castro Osvaldo²¹,Nör Carolina²²,Taylor Michael D²²,Young Leonie S²³,Varešlija Damir²³^ORCID,Cosgrove Nicola²³,Couch Fergus J²⁴,Cussó Lorena²⁵²⁶²⁷²⁸,Desco Manuel²⁵²⁶²⁷²⁸,Mouron Silvana²⁹,Quintela‐Fandino Miguel²⁹,Weller Michael⁸,Pastor Joaquín²,Valiente Manuel¹^ORCID,de la Lama‐Zaragoza Adolfo^ORCID,Calero‐Felix Lourdes,Fiaño‐Valverde Concepcion,Delgado‐López Pedro David,Montalvo‐Afonso Antonio,Pascual‐Llorente Mar,Díaz‐Piqueras Ángela,Nam‐Cha SH,Barrena López Cristina,Plans Ahicart Gerard,Martínez‐Saez Elena,Ramón y Cajal Santiago,Nicolás Pilar,

Affiliation:

1. Brain Metastasis Group CNIO Madrid Spain

2. Experimental Therapeutics Programme CNIO Madrid Spain

3. Biobank CNIO Madrid Spain

4. Molecular Cytogenetics Unit CNIO Madrid Spain

5. Division of Hematopoietic Innovative Therapies Centro de Investigaciones Energeticas Medioambientales y Tecnologicas (CIEMAT) Madrid Spain

6. Department of Neuro‐Oncology University and City of Health and Science Hospital Turin Italy

7. Department of Medical Sciences University of Turin Turin Italy

8. Department of Neurology Clinical Neuroscience Center University Hospital Zurich and University of Zurich Zurich Switzerland

9. Proteomics Unit ProteoRedISCIII CNIO Madrid Spain

10. Neuro‐Oncology Unit Hospital Universitario 12 de Octubre Madrid Spain

11. Neurosurgery Unit Hospital Universitario 12 de Octubre Madrid Spain

12. Department of Surgery Universidad Complutense de Madrid Madrid Spain

13. Neuropathology Unit Instituto i+12, Hospital Universitario 12 de Octubre Madrid Spain

14. Neuro‐Oncology Group Research Institute Hospital 12 de Octubre (i+12) Madrid Spain

15. Pathology Department Instituto i+12, Hospital Universitario 12 de Octubre Madrid Spain

16. Universidad Francisco de Vitoria Madrid Spain

17. Neurosurgery Department Hospital Universitario de La Princesa Madrid Spain

18. Histopathology Unit CNIO Madrid Spain

19. Department of Anatomy and Cell Biology and Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED) University of Cantabria‐IDIVAL Santander Spain

20. Confocal Microscopy Unit CNIO Madrid Spain

21. Bioinformatics Unit CNIO Madrid Spain

22. Developmental and Stem Cell Biology Program and The Arthur and Sonia Labatt Brain Tumour Research Centre The Hospital for Sick Children Toronto ON Canada

23. Endocrine Oncology Research Group Department of Surgery RCSI University of Medicine and Health Sciences Dublin Ireland

24. Department of Laboratory Medicine and Pathology Mayo Clinic Rochester MN USA

25. Departamento de Bioingeniería e Ingeniería Aeroespacial Universidad Carlos III de Madrid Madrid Spain

26. Instituto de Investigación Sanitaria Gregorio Marañón Madrid Spain

27. Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM) Madrid Spain

28. Unidad de Imagen Avanzada Centro Nacional de Investigaciones Cardiovasculares (CNIC) Madrid Spain

29. Breast Cancer Clinical Research Unit CNIO Madrid Spain

Funder

Ministerio de Economía, Industria y Competitividad, Gobierno de España

Fundació la Marató de TV3

Melanoma Research Alliance

Fundación Ramón Areces

Worldwide Cancer Research

Cancer Research Institute

Fundación Científica Asociación Española Contra el Cáncer

H2020 European Research Council

Comunidad de Madrid

Instituto de Salud Carlos III

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.202114552

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