Methionine metabolism is essential for SIRT 1‐regulated mouse embryonic stem cell maintenance and embryonic development

Author:

Tang Shuang1,Fang Yi1,Huang Gang23,Xu Xiaojiang4,Padilla‐Banks Elizabeth5,Fan Wei1,Xu Qing1,Sanderson Sydney M6,Foley Julie F7,Dowdy Scotty7,McBurney Michael W8,Fargo David C4,Williams Carmen J5ORCID,Locasale Jason W6ORCID,Guan Ziqiang9,Li Xiaoling1ORCID

Affiliation:

1. Signal Transduction Laboratory National Institute of Environmental Health Sciences Research Triangle Park NC USA

2. Department of Nuclear Medicine Ren Ji Hospital School of Medicine Shanghai Jiao Tong University Shanghai China

3. Shanghai University of Medicine & Health Sciences Shanghai China

4. Integrative Bioinformatics National Institute of Environmental Health Sciences Research Triangle Park NC USA

5. Reproductive and Developmental Biology Laboratory National Institute of Environmental Health Sciences Research Triangle Park NC USA

6. Department of Pharmacology and Cancer Biology Duke Cancer Institute Duke Molecular Physiology Institute Duke University School of Medicine Durham NC USA

7. Cellular and Molecular Pathology Branch and Comparative Medicine Branch National Institute of Environmental Health Sciences Research Triangle Park NC USA

8. Program for Cancer Therapeutics Ottawa Hospital Research Institute Ottawa ON Canada

9. Department of Biochemistry Duke University Medical Center Durham NC USA

Funder

National Institutes of Health

Office of Extramural Research, National Institutes of Health

National Natural Science Foundation of China

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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