Affiliation:
1. Department of Radiation Protection Medicine, School of Military Preventive Medicine, Air Force Medical University, Xi’an, China
2. Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Xi’an, China
3. Department of Urology, Xijing Hospital, Air Force Medical University, Xi’an, China
Abstract
Objective. To investigate the effects of exposure to 5.8 GHz microwaves on testicular structure and function of male adult rats. Methods. After 30 days of exposure, we evaluated sperm quality by determining sperm concentration and quantifying the number of abnormal sperm. Testicular morphology was investigated by hematoxylin-eosin (HE) staining. The levels of testosterone (T), follicle-stimulating hormone (FSH), luteinizing hormone (LH), glial cell line-derived neurotrophic factor (GDNF), stem cell factor (SCF), and transferrin (TRF) were determined by enzyme-linked immunosorbent assays (ELISAs). We also used western blotting to determine the levels of GDNF and SCF and apoptosis-related protein (caspase-3) in the testis. Results. Compared with the sham group, there were no significant differences in terms of sperm count, sperm abnormality, and the levels of T, FSH, LH, GDNF, SCF, and caspase-3 in the microwave group. Conclusion. Under the experimental conditions, 5.8 GHz microwave exposure has no obvious effect on testicular structure and function of rats.
Funder
National Natural Science Foundation of China
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
5 articles.
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