1. Microscopic Image and Medical Image Analysis Group, College of Medicine and Biological Information Engineering, Northeastern University, Shenyang 110169, China
2. Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang 110042, China
3. Control Engineering College, Chengdu University of Information Technology, Chengdu 610103, China
4. Institute of Medical Informatics, University of Luebeck, Luebeck, Germany
5. Shenyang Institute of Automation, Chinese Academy of Sciences, 110169, China
6. Department of Electrical and Computer Engineering, Stevens Institute of Technology, Hoboken, NJ 07030, USA