Auxiliary Segmentation Method of Osteosarcoma MRI Image Based on Transformer and U-Net

Author:

Liu Feng12,Zhu Jun34ORCID,Lv Baolong5ORCID,Yang Lei6,Sun Wenyan1,Dai Zhehao7ORCID,Gou Fangfang8,Wu Jia89ORCID

Affiliation:

1. School of Information Engineering, Shandong Youth University of Political Science, Jinan, Shandong, China

2. New Technology Research and Development Center of Intelligent Information Controlling in Universities of Shandong, Jinan 250103, China

3. The First People’s Hospital of Huaihua, Huaihua 418000, Hunan, China

4. Collaborative Innovation Center for Medical Artificial Intelligence and Big Data Decision Making Assistance, Hunan University of Medicine, Huaihua 418000, Hunan, China

5. School of Modern Service Management, Shandong Youth University of Political Science, Jinan, China

6. School of Computer Science and Technology, Shandong Janzhu University, Jinan, China

7. Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, China

8. School of Computer Science and Engineering, Central South University, Changsha 410083, China

9. Research Center for Artificial Intelligence, Monash University, Melbourne, Clayton, Victoria 3800, Australia

Abstract

One of the most prevalent malignant bone tumors is osteosarcoma. The diagnosis and treatment cycle are long and the prognosis is poor. It takes a lot of time to manually identify osteosarcoma from osteosarcoma magnetic resonance imaging (MRI). Medical image processing technology has greatly alleviated the problems faced by medical diagnoses. However, MRI images of osteosarcoma are characterized by high noise and blurred edges. The complex features increase the difficulty of lesion area identification. Therefore, this study proposes an osteosarcoma MRI image segmentation method (OSTransnet) based on Transformer and U-net. This technique primarily addresses the issues of fuzzy tumor edge segmentation and overfitting brought on by data noise. First, we optimize the dataset by changing the precise spatial distribution of noise and the data-increment image rotation process. The tumor is then segmented based on the model of U-Net and Transformer with edge improvement. It compensates for the limitations of U-semantic Net by using channel-based transformers. Finally, we also add an edge enhancement module (BAB) and a combined loss function to improve the performance of edge segmentation. The method’s accuracy and stability are demonstrated by the detection and training results based on more than 4,000 MRI images of osteosarcoma, which also demonstrate how well the method works as an adjunct to clinical diagnosis and treatment.

Funder

Focus on Research and Development Projects in Shandong Province

Publisher

Hindawi Limited

Subject

General Mathematics,General Medicine,General Neuroscience,General Computer Science

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