Salivary Distinctiveness and Modifications in Males with Diabetes and Behçet’s Disease

Author:

Aljerf Loai1ORCID,Alhaffar Iyad2

Affiliation:

1. Department of Life Sciences, Faculty of Dentistry, University of Damascus, Damascus, Syria

2. Department of Oral Medicine, Faculty of Dentistry, University of Damascus, Damascus, Syria

Abstract

Oral diseases associated with systematic diseases as metabolic and vasculitic have been included in this paper. This will enhance our understanding of the salivary function in promoting healthy oral condition. The study investigates the effects of type I and type II diabetes mellitus in well-controlled diabetic patients, in addition toBehçet disease (BD)on saliva flow rate (SFR), pH, the decay, missing, and filled tooth (DMFT) index, glucose, and major earth-alkaline ions (Ca2+and Mg2+) compared to healthy males and age-matched controls. Saliva samples were collected from 1403 male human subjects, distributed on 7 levels including 3 control groups, and analyzed. The symptoms and clinical observations were enrolled. A preprandial salivary glucose has illustrated statistically strong significant and positive correlations withHbA1cand blood glucose levels. TIDM saliva showed lower pH, SFR, and Ca2+but higher Mg2+, caries risk, and poor metabolic control. These led to dysfunction of secretory capacity of salivary glands. TIIDM proved higher SFR, DMFT, and glucose than TIDM patients. DM oral calcium has decreased by age while magnesium sharply slopes at seniority. BD oral fluid is associated with lower glucose and minerals but noticeably with both higher pH and DMFT.

Funder

Deanship of the Faculty of Dentistry

Publisher

Hindawi Limited

Subject

Biochemistry

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